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SYRE correlations (Spyre Therapeutics, Inc.)

SYRE measured against 4756 US stocks and ETFs: closest co-movers on one side, the best offsets on the other, all from weekly returns.

Data as of 2026-08-27 · refreshed every trading day · US Listed

Volatility (ann.)
83.8%
3y weekly
Beta vs S&P 500
1.80
3y weekly
1-year return
+446.2%
price, adjusted
5-year return
-47.5%
price, adjusted
Market cap
$8.3B
latest
Max drawdown
-74.0%
3y, daily closes
-12%0%+526%2025-09-052026-08-27
SYRE over the last 12 months, weekly closes indexed to 100 at the start.

Stocks and ETFs most correlated with SYRE

AssetCorrelation (3Y)
VVOSVivos Therapeutics, Inc.0.49
APGEApogee Therapeutics, Inc.0.48
ARTVArtiva Biotherapeutics, Inc.0.48
XBISPDR S&P Biotech ETF0.45
LMNRLimoneira Co0.44

Best diversifiers for SYRE

If the goal is offsetting SYRE, these tracked assets have historically moved the most on their own terms.

AssetCorrelation (3Y)
VXXiPath Series B S&P 500 VIX Short-Term Futures ETN-0.26
CENNCenntro Inc.-0.26
VXZiPath Series B S&P 500 VIX Mid-Term Futures ETN-0.23

SYRE vs benchmarks

Get SYRE data as JSON

Free API · no key required
$ curl https://www.pairbook.io/api/v1/symbols/syre.json

Correlations, diversifiers, beta and volatility for SYRE, plus one endpoint per pair. API documentation.

SYRE inside major ETFs

ETFSYRE weight
IBBiShares Biotechnology ETF0.5%
IWMiShares Russell 2000 ETF0.22%