ARTV vs SYRE: Correlation
Artiva Biotherapeutics, Inc. (ARTV) and Spyre Therapeutics, Inc. (SYRE) show a moderate relationship: their 3-year correlation of weekly returns is 0.48.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are ARTV and SYRE?
Over the past 3 years, ARTV and SYRE moved with a correlation of 0.48, which is moderate. The relationship has been stable: the 1-year correlation (0.50) sits close to the 3-year figure. Over 5 years the correlation is n/a, and the annualized covariance of weekly returns is 4585.5 %².
Within ARTV's tracked universe of 19 assets, SYRE comes in at #5 by 3-year correlation. Correlation aside, the last 12 months split them widely, with SYRE ahead by 181.1 points (+265.1% versus +446.2%). One caveat on sizing: ARTV is 1.7 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
ARTV vs SYRE: side by side
| ARTV (Artiva Biotherapeutics, Inc.) | SYRE (Spyre Therapeutics, Inc.) | |
|---|---|---|
| 1-year return | +265.1% | +446.2% |
| 5-year return | n/a | -47.5% |
| Volatility (ann.) | 145.0% | 83.8% |
| Beta vs S&P 500 | 2.62 | 1.80 |
| Max drawdown (3Y) | -90.7% | -74.0% |
| Market cap | $0.6B | $8.3B |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | ARTV | SYRE |
|---|---|---|
| 2022 | – | -90.5% |
| 2023 | – | +91.3% |
| 2024 | – | +8.2% |
| 2025 | -57.4% | +40.7% |
| 2026 | +178.3% | +185.8% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are ARTV and SYRE good diversifiers for each other?
Yes, to a useful degree: a correlation of 0.48 leaves real independence between the two, which historically damped combined volatility.
FAQ
What is the correlation between ARTV and SYRE?
Using weekly returns as of 2026-08-27: 0.48 over 3 years, with 0.50 over the last year and n/a over 5 years.
Is SYRE a good diversifier for ARTV?
Yes, to a useful degree: a correlation of 0.48 leaves real independence between the two, which historically damped combined volatility.
What does a correlation of 0.48 mean?
On the −1 to +1 scale, 0.48 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/artv-vs-syre.json
Embed this badge (it refreshes with the data), with attribution:
[](https://www.pairbook.io/pair/artv-vs-syre/)
No key needed, free to use. Full endpoint list in the API documentation.
Related comparisons
Hubs: ARTV correlations · SYRE correlations
