RYTM vs XBI: Correlation
Rhythm Pharmaceuticals, Inc. (RYTM) and SPDR S&P Biotech ETF (XBI) show a moderate relationship: their 3-year correlation of weekly returns is 0.59.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are RYTM and XBI?
On 3 years of weekly data the RYTM/XBI correlation comes out at 0.59, moderate. Recent behaviour matches the longer record: 0.64 over 1 year against 0.59 over 3. The 5-year figure is 0.40, and annualized covariance runs at 958.8 %².
In RYTM's tracked universe of 13 assets, XBI sits right near the top at #1. Correlation aside, the last 12 months split them widely, with XBI ahead by 77.2 points (+10.0% versus +87.2%). One caveat on sizing: RYTM is 2.1 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
RYTM vs XBI: side by side
| RYTM (Rhythm Pharmaceuticals, Inc.) | XBI (SPDR S&P Biotech ETF) | |
|---|---|---|
| 1-year return | +10.0% | +87.2% |
| 5-year return | +785.4% | +28.6% |
| Volatility (ann.) | 58.4% | 27.7% |
| Beta vs S&P 500 | 1.92 | 1.09 |
| Max drawdown (3Y) | -35.5% | -33.0% |
| Market cap | $7.7B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | – |
| Sector / category | US Listed | ETF · Thematic |
Year-by-year returns
| Year | RYTM | XBI |
|---|---|---|
| 2022 | +191.8% | -25.9% |
| 2023 | +57.9% | +7.6% |
| 2024 | +21.8% | +1.0% |
| 2025 | +91.2% | +35.9% |
| 2026 | +5.1% | +38.1% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are RYTM and XBI good diversifiers for each other?
To a limited degree. At 0.59 the two still catch most of the same waves, so the pair smooths returns a little without insulating either from a shared selloff.
FAQ
What is the correlation between RYTM and XBI?
As of 2026-08-27, the correlation of weekly returns between RYTM and XBI is 0.59 over 3 years, 0.64 over 1 year and 0.40 over 5 years.
Is XBI a good diversifier for RYTM?
To a limited degree. At 0.59 the two still catch most of the same waves, so the pair smooths returns a little without insulating either from a shared selloff.
What does a correlation of 0.59 mean?
On the −1 to +1 scale, 0.59 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/rytm-vs-xbi.json
Embed this badge (it refreshes with the data), with attribution:
[](https://www.pairbook.io/pair/rytm-vs-xbi/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: RYTM correlations · XBI correlations
