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IBB vs RYTM: Correlation

How closely do iShares Biotechnology ETF (IBB) and Rhythm Pharmaceuticals, Inc. (RYTM) trade together? Their weekly returns over three years give a correlation of 0.53, which is moderate.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.53
moderate
Correlation (1Y)
0.51
last 12 months
Correlation (5Y)
0.31
long-run
Ann. covariance
637.5
%² · weekly, annualized

How correlated are IBB and RYTM?

Across a 3-year window, the weekly returns of IBB and RYTM correlate at 0.53, moderate. Recent behaviour matches the longer record: 0.51 over 1 year against 0.53 over 3. Stretching to 5 years gives 0.31, with an annualized covariance of 637.5 %².

Among the 168 assets we track against IBB, RYTM ranks #77 by 3-year correlation. The last year tells two different stories: IBB led by 45.4 percentage points, +55.4% for IBB against +10.0% for RYTM. Risk is not evenly split, since RYTM carries 2.8 times the volatility of the other side.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

IBB vs RYTM: side by side

IBB (iShares Biotechnology ETF)RYTM (Rhythm Pharmaceuticals, Inc.)
1-year return+55.4%+10.0%
5-year return+26.6%+785.4%
Volatility (ann.)20.7%58.4%
Beta vs S&P 5000.811.92
Max drawdown (3Y)-24.9%-35.5%
Market cap$7.7B
P/E (trailing)
Dividend yield0.22%0.00%
Expense ratio0.44%
Assets under management$9.2B
Sector / categoryETF · ThematicUS Listed
Higher yield: IBB 0.22% vs 0.00%Smaller drawdown: IBB -24.9% vs -35.5%Higher 5y return: RYTM +785.4% vs +26.6%

On the fund side, IBB sits in the Health category at iShares, with $9.2B under management, 235 holdings, a 0.44% expense ratio, a 0.22% trailing dividend yield.

-26%0%+50%2025-09-052026-08-27
Twelve months of weekly closes, each series rebased to 100. IBB · RYTM

Year-by-year returns

YearIBBRYTM
2022-13.7%+191.8%
2023+3.8%+57.9%
2024-2.4%+21.8%
2025+28.0%+91.2%
2026+27.4%+5.1%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Fund exposure

A structural note: 0.51% of IBB is RYTM itself, so the fund partly moves with the stock by construction.

Are IBB and RYTM good diversifiers for each other?

To a limited degree. At 0.53 the two still catch most of the same waves, so the pair smooths returns a little without insulating either from a shared selloff.

FAQ

What is the correlation between IBB and RYTM?

As of 2026-08-27, the correlation of weekly returns between IBB and RYTM is 0.53 over 3 years, 0.51 over 1 year and 0.31 over 5 years.

Is RYTM a good diversifier for IBB?

To a limited degree. At 0.53 the two still catch most of the same waves, so the pair smooths returns a little without insulating either from a shared selloff.

What does a correlation of 0.53 mean?

On the −1 to +1 scale, 0.53 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.

Use this data

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IBB vs RYTM: 3-year weekly correlation 0.53IBB vs RYTM0.53

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Related comparisons

Hubs: IBB correlations · RYTM correlations