XBI correlations (SPDR S&P Biotech ETF)
XBI measured against 4756 US stocks and ETFs: closest co-movers on one side, the best offsets on the other, all from weekly returns.
Data as of 2026-08-27 · refreshed every trading day · Thematic
Volatility (ann.)
27.7%
3y weekly
Beta vs S&P 500
1.09
3y weekly
1-year return
+87.2%
price, adjusted
5-year return
+28.6%
price, adjusted
Max drawdown
-33.0%
3y, daily closes
XBI over the last 12 months, weekly closes indexed to 100 at the start.
Stocks and ETFs most correlated with XBI
| Asset | Correlation (3Y) | ||
|---|---|---|---|
| IBB | iShares Biotechnology ETF | 0.92 | |
| HQL | abrdn Life Sciences Investors Shares of Beneficial Interest | 0.84 | |
| HQH | abrdn Healthcare Investors Shares of Beneficial Interest | 0.80 | |
| DNLI | Denali Therapeutics Inc. | 0.74 | |
| BMEZ | BlackRock Health Sciences Term Trust | 0.73 | |
| IDYA | IDEAYA Biosciences, Inc. | 0.73 | |
| IWM | iShares Russell 2000 ETF | 0.72 | |
| BME | Blackrock Health Sciences Trust | 0.68 | |
| BEAM | Beam Therapeutics Inc. | 0.68 | |
| RLAY | Relay Therapeutics, Inc. | 0.68 | |
| NRIX | Nurix Therapeutics, Inc. | 0.67 | |
| CLDX | Celldex Therapeutics, Inc. | 0.66 | |
| TWST | Twist Bioscience Corporation | 0.66 | |
| KYMR | Kymera Therapeutics, Inc. | 0.66 | |
| SNDX | Syndax Pharmaceuticals, Inc. | 0.65 |
Best diversifiers for XBI
The least-correlated liquid assets in our universe, meaning the ones that historically moved most independently from XBI.
| Asset | Correlation (3Y) | ||
|---|---|---|---|
| VXZ | iPath Series B S&P 500 VIX Mid-Term Futures ETN | -0.52 | |
| VXX | iPath Series B S&P 500 VIX Short-Term Futures ETN | -0.52 | |
| FNGD | MicroSectors FANG Index -3X Inverse Leveraged ETNs due | -0.43 | |
| BTCT | BTC Digital Ltd. | -0.21 | |
| EQNR | Equinor ASA | -0.21 | |
| IBAC | IB Acquisition Corp. | -0.18 | |
| ASST | Strive, Inc. | -0.16 | |
| USO | United States Oil Fund | -0.16 | |
| JL | J-Long Group Limited - Class A | -0.14 | |
| MVST | Microvast Holdings, Inc. | -0.14 |
XBI vs benchmarks
XBI vs its peers
Get XBI data as JSON
$ curl https://www.pairbook.io/api/v1/symbols/xbi.jsonCorrelations, diversifiers, beta and volatility for XBI, plus one endpoint per pair. API documentation.
