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CLDX vs XBI: Correlation

How closely do Celldex Therapeutics, Inc. (CLDX) and SPDR S&P Biotech ETF (XBI) trade together? Their weekly returns over three years give a correlation of 0.66, which is strong.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.66
strong
Correlation (1Y)
0.49
last 12 months
Correlation (5Y)
0.67
long-run
Ann. covariance
1085.5
%² · weekly, annualized

How correlated are CLDX and XBI?

On 3 years of weekly data the CLDX/XBI correlation comes out at 0.66, strong. The link has loosened recently: the 1-year correlation (0.49) runs below the 3-year figure (0.66). The 5-year figure is 0.67, and annualized covariance runs at 1085.5 %².

In CLDX's tracked universe of 18 assets, XBI sits right near the top at #1. On 12-month performance XBI holds a 8.2-point edge, +79.0% against +87.2%. Risk is not evenly split, since CLDX carries 2.1 times the volatility of the other side.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

CLDX vs XBI: side by side

CLDX (Celldex Therapeutics, Inc.)XBI (SPDR S&P Biotech ETF)
1-year return+79.0%+87.2%
5-year return-21.9%+28.6%
Volatility (ann.)59.4%27.7%
Beta vs S&P 5001.481.09
Max drawdown (3Y)-70.8%-33.0%
Market cap$3.2B
P/E (trailing)
Dividend yield0.00%
Sector / categoryUS ListedETF · Thematic
Smaller drawdown: XBI -33.0% vs -70.8%Higher 5y return: XBI +28.6% vs -21.9%
-1%0%+83%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. CLDX · XBI

Year-by-year returns

YearCLDXXBI
2022+15.3%-25.9%
2023-11.0%+7.6%
2024-36.3%+1.0%
2025+7.5%+35.9%
2026+49.0%+38.1%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are CLDX and XBI good diversifiers for each other?

Only partially. A correlation of 0.66 means CLDX and XBI share most of their swings. Pairing them dampens volatility somewhat, but it will not protect against a common drawdown.

FAQ

What is the correlation between CLDX and XBI?

As of 2026-08-27, the correlation of weekly returns between CLDX and XBI is 0.66 over 3 years, 0.49 over 1 year and 0.67 over 5 years.

Is XBI a good diversifier for CLDX?

Only partially. A correlation of 0.66 means CLDX and XBI share most of their swings. Pairing them dampens volatility somewhat, but it will not protect against a common drawdown.

What does a correlation of 0.66 mean?

On the −1 to +1 scale, 0.66 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.

Use this data

JSON API · no key required
$ curl https://www.pairbook.io/api/v1/pairs/cldx-vs-xbi.json

CLDX vs XBI: 3-year weekly correlation 0.66CLDX vs XBI0.66

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Related comparisons

Hubs: CLDX correlations · XBI correlations