RYTM vs SNDX: Correlation
Rhythm Pharmaceuticals, Inc. (RYTM) and Syndax Pharmaceuticals, Inc. (SNDX) show a moderate relationship: their 3-year correlation of weekly returns is 0.53.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are RYTM and SNDX?
Across a 3-year window, the weekly returns of RYTM and SNDX correlate at 0.53, moderate. Lately the two have drifted apart, with the 1-year correlation at 0.34 versus 0.53 over 3 years. Stretching to 5 years gives 0.38, with an annualized covariance of 1776.7 %².
Among the 13 assets we track against RYTM, SNDX ranks #5 by 3-year correlation. The trailing year gives SNDX the advantage: +10.0% versus +24.0%, a 14.0-point spread.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
RYTM vs SNDX: side by side
| RYTM (Rhythm Pharmaceuticals, Inc.) | SNDX (Syndax Pharmaceuticals, Inc.) | |
|---|---|---|
| 1-year return | +10.0% | +24.0% |
| 5-year return | +785.4% | +16.9% |
| Volatility (ann.) | 58.4% | 57.8% |
| Beta vs S&P 500 | 1.92 | 1.25 |
| Max drawdown (3Y) | -35.5% | -64.8% |
| Market cap | $7.7B | $1.8B |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | RYTM | SNDX |
|---|---|---|
| 2022 | +191.8% | +16.3% |
| 2023 | +57.9% | -15.1% |
| 2024 | +21.8% | -38.8% |
| 2025 | +91.2% | +58.9% |
| 2026 | +5.1% | -4.0% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are RYTM and SNDX good diversifiers for each other?
Only partially. A correlation of 0.53 means RYTM and SNDX share most of their swings. Pairing them dampens volatility somewhat, but it will not protect against a common drawdown.
FAQ
What is the correlation between RYTM and SNDX?
As of 2026-08-27, the correlation of weekly returns between RYTM and SNDX is 0.53 over 3 years, 0.34 over 1 year and 0.38 over 5 years.
Is SNDX a good diversifier for RYTM?
Only partially. A correlation of 0.53 means RYTM and SNDX share most of their swings. Pairing them dampens volatility somewhat, but it will not protect against a common drawdown.
What does a correlation of 0.53 mean?
On the −1 to +1 scale, 0.53 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/rytm-vs-sndx.json
Embed this badge (it refreshes with the data), with attribution:
[](https://www.pairbook.io/pair/rytm-vs-sndx/)
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Related comparisons
Hubs: RYTM correlations · SNDX correlations
