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RYTM vs VXZ: Correlation

How closely do Rhythm Pharmaceuticals, Inc. (RYTM) and iPath Series B S&P 500 VIX Mid-Term Futures ETN (VXZ) trade together? Their weekly returns over three years give a correlation of -0.38, which is negative.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
-0.38
negative
Correlation (1Y)
-0.35
last 12 months
Correlation (5Y)
-0.20
long-run
Ann. covariance
-567.4
%² · weekly, annualized

How correlated are RYTM and VXZ?

Across a 3-year window, the weekly returns of RYTM and VXZ correlate at -0.38, negative, meaning they tend to move in opposite directions. The relationship has been stable: the 1-year correlation (-0.35) sits close to the 3-year figure. Stretching to 5 years gives -0.20, with an annualized covariance of -567.4 %².

Out of 13 assets tracked against RYTM, VXZ lands near the bottom at #12. Correlation aside, the last 12 months split them widely, with RYTM ahead by 26.1 points (+10.0% versus -16.1%). Risk is not evenly split, since RYTM carries 2.3 times the volatility of the other side.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

RYTM vs VXZ: side by side

RYTM (Rhythm Pharmaceuticals, Inc.)VXZ (iPath Series B S&P 500 VIX Mid-Term Futures ETN)
1-year return+10.0%-16.1%
5-year return+785.4%-53.1%
Volatility (ann.)58.4%25.6%
Beta vs S&P 5001.92-1.31
Max drawdown (3Y)-35.5%-36.4%
Market cap$7.7B
P/E (trailing)
Dividend yield0.00%
Sector / categoryUS ListedUS Listed
Smaller drawdown: RYTM -35.5% vs -36.4%Higher 5y return: RYTM +785.4% vs -53.1%
-26%0%+13%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. RYTM · VXZ

Year-by-year returns

YearRYTMVXZ
2022+191.8%+0.5%
2023+57.9%-44.0%
2024+21.8%-12.7%
2025+91.2%+5.7%
2026+5.1%-10.5%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are RYTM and VXZ good diversifiers for each other?

Yes: at -0.38, the two have gone their own ways historically, which is what genuine diversification looks like.

FAQ

What is the correlation between RYTM and VXZ?

Using weekly returns as of 2026-08-27: -0.38 over 3 years, with -0.35 over the last year and -0.20 over 5 years.

Is VXZ a good diversifier for RYTM?

Yes: at -0.38, the two have gone their own ways historically, which is what genuine diversification looks like.

What does a correlation of -0.38 mean?

On the −1 to +1 scale, -0.38 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.

Use this data

JSON API · no key required
$ curl https://www.pairbook.io/api/v1/pairs/rytm-vs-vxz.json

RYTM vs VXZ: 3-year weekly correlation -0.38RYTM vs VXZ-0.38

Drop this badge in a README or notebook; it updates with the data:

[![RYTM vs VXZ correlation](https://www.pairbook.io/api/v1/badge/rytm-vs-vxz.svg)](https://www.pairbook.io/pair/rytm-vs-vxz/)

The core API is free. Terms and every endpoint in the API documentation.

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Hubs: RYTM correlations · VXZ correlations