DSGN vs XBI: Correlation
Design Therapeutics, Inc. (DSGN) and SPDR S&P Biotech ETF (XBI) show a moderate relationship: their 3-year correlation of weekly returns is 0.46.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are DSGN and XBI?
Over the past 3 years, DSGN and XBI moved with a correlation of 0.46, which is moderate. The relationship has been stable: the 1-year correlation (0.39) sits close to the 3-year figure. Over 5 years the correlation is 0.49, and the annualized covariance of weekly returns is 915.7 %².
XBI is one of the assets that tracks DSGN most closely: it ranks #1 out of the 11 assets we track against DSGN. Their recent paths diverged sharply: over the last 12 months DSGN outperformed by 101.1 percentage points (+188.3% for DSGN against +87.2% for XBI). Risk is not evenly split, since DSGN carries 2.6 times the volatility of the other side.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
DSGN vs XBI: side by side
| DSGN (Design Therapeutics, Inc.) | XBI (SPDR S&P Biotech ETF) | |
|---|---|---|
| 1-year return | +188.3% | +87.2% |
| 5-year return | +0.7% | +28.6% |
| Volatility (ann.) | 72.7% | 27.7% |
| Beta vs S&P 500 | 1.35 | 1.09 |
| Max drawdown (3Y) | -62.8% | -33.0% |
| Market cap | $1.0B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | – |
| Sector / category | US Listed | ETF · Thematic |
Year-by-year returns
| Year | DSGN | XBI |
|---|---|---|
| 2022 | -52.1% | -25.9% |
| 2023 | -74.2% | +7.6% |
| 2024 | +132.8% | +1.0% |
| 2025 | +52.0% | +35.9% |
| 2026 | +62.6% | +38.1% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are DSGN and XBI good diversifiers for each other?
A fair diversifier. At 0.46, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
FAQ
What is the correlation between DSGN and XBI?
As of 2026-08-27, the correlation of weekly returns between DSGN and XBI is 0.46 over 3 years, 0.39 over 1 year and 0.49 over 5 years.
Is XBI a good diversifier for DSGN?
A fair diversifier. At 0.46, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
What does a correlation of 0.46 mean?
A reading of 0.46 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
Use this data
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Related comparisons
Hubs: DSGN correlations · XBI correlations
