DSGN vs IBB: Correlation
Measured on weekly returns over the past three years, Design Therapeutics, Inc. (DSGN) and iShares Biotechnology ETF (IBB) carry a correlation of 0.44, a moderate link.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are DSGN and IBB?
Over the past 3 years, DSGN and IBB moved with a correlation of 0.44, which is moderate. Lately the two have drifted apart, with the 1-year correlation at 0.29 versus 0.44 over 3 years. Over 5 years the correlation is 0.44, and the annualized covariance of weekly returns is 658.8 %².
Within DSGN's tracked universe of 11 assets, IBB comes in at #4 by 3-year correlation. Their recent paths diverged sharply: over the last 12 months DSGN outperformed by 132.9 percentage points (+188.3% for DSGN against +55.4% for IBB). Note the risk asymmetry: DSGN runs 3.5 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
DSGN vs IBB: side by side
| DSGN (Design Therapeutics, Inc.) | IBB (iShares Biotechnology ETF) | |
|---|---|---|
| 1-year return | +188.3% | +55.4% |
| 5-year return | +0.7% | +26.6% |
| Volatility (ann.) | 72.7% | 20.7% |
| Beta vs S&P 500 | 1.35 | 0.81 |
| Max drawdown (3Y) | -62.8% | -24.9% |
| Market cap | $1.0B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.22% |
| Expense ratio | – | 0.44% |
| Assets under management | – | $9.2B |
| Sector / category | US Listed | ETF · Thematic |
IBB, iShares's Health fund, carries $9.2B under management, 235 holdings, a 0.44% expense ratio, a 0.22% trailing dividend yield.
Year-by-year returns
| Year | DSGN | IBB |
|---|---|---|
| 2022 | -52.1% | -13.7% |
| 2023 | -74.2% | +3.8% |
| 2024 | +132.8% | -2.4% |
| 2025 | +52.0% | +28.0% |
| 2026 | +62.6% | +27.4% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are DSGN and IBB good diversifiers for each other?
A fair diversifier. At 0.44, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
FAQ
What is the correlation between DSGN and IBB?
Using weekly returns as of 2026-08-27: 0.44 over 3 years, with 0.29 over the last year and 0.44 over 5 years.
Is IBB a good diversifier for DSGN?
A fair diversifier. At 0.44, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
What does a correlation of 0.44 mean?
A reading of 0.44 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/dsgn-vs-ibb.json
Embed this badge (it refreshes with the data), with attribution:
[](https://www.pairbook.io/pair/dsgn-vs-ibb/)
No key needed, free to use. Full endpoint list in the API documentation.
Related comparisons
Hubs: DSGN correlations · IBB correlations
