DSGN vs VXZ: Correlation
Design Therapeutics, Inc. (DSGN) and iPath Series B S&P 500 VIX Mid-Term Futures ETN (VXZ) show a negative relationship: their 3-year correlation of weekly returns is -0.29.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are DSGN and VXZ?
Across a 3-year window, the weekly returns of DSGN and VXZ correlate at -0.29, negative, meaning they tend to move in opposite directions. Lately the two have moved closer together, with the 1-year correlation at -0.15 versus -0.29 over 3 years. Stretching to 5 years gives -0.28, with an annualized covariance of -542.1 %².
Among the 11 assets we track against DSGN, VXZ sits near the bottom by co-movement, at rank #10. Correlation aside, the last 12 months split them widely, with DSGN ahead by 204.4 points (+188.3% versus -16.1%). Note the risk asymmetry: DSGN runs 2.8 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
DSGN vs VXZ: side by side
| DSGN (Design Therapeutics, Inc.) | VXZ (iPath Series B S&P 500 VIX Mid-Term Futures ETN) | |
|---|---|---|
| 1-year return | +188.3% | -16.1% |
| 5-year return | +0.7% | -53.1% |
| Volatility (ann.) | 72.7% | 25.6% |
| Beta vs S&P 500 | 1.35 | -1.31 |
| Max drawdown (3Y) | -62.8% | -36.4% |
| Market cap | $1.0B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | – |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | DSGN | VXZ |
|---|---|---|
| 2022 | -52.1% | +0.5% |
| 2023 | -74.2% | -44.0% |
| 2024 | +132.8% | -12.7% |
| 2025 | +52.0% | +5.7% |
| 2026 | +62.6% | -10.5% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are DSGN and VXZ good diversifiers for each other?
Yes. With a correlation of -0.29, DSGN and VXZ have moved largely independently, which makes them a genuinely diversifying pair by historical standards.
FAQ
What is the correlation between DSGN and VXZ?
As of 2026-08-27, the correlation of weekly returns between DSGN and VXZ is -0.29 over 3 years, -0.15 over 1 year and -0.28 over 5 years.
Is VXZ a good diversifier for DSGN?
Yes. With a correlation of -0.29, DSGN and VXZ have moved largely independently, which makes them a genuinely diversifying pair by historical standards.
What does a correlation of -0.29 mean?
A reading of -0.29 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/dsgn-vs-vxz.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/dsgn-vs-vxz/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: DSGN correlations · VXZ correlations
