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DSGN vs QQQ: Correlation

How closely do Design Therapeutics, Inc. (DSGN) and Invesco QQQ Trust (QQQ) trade together? Their weekly returns over three years give a correlation of 0.21, which is weak.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.21
weak
Correlation (1Y)
0.18
last 12 months
Correlation (5Y)
0.29
long-run
Ann. covariance
296.8
%² · weekly, annualized

How correlated are DSGN and QQQ?

Across a 3-year window, the weekly returns of DSGN and QQQ correlate at 0.21, weak. The relationship has been stable: the 1-year correlation (0.18) sits close to the 3-year figure. Stretching to 5 years gives 0.29, with an annualized covariance of 296.8 %².

QQQ is close to the least connected end of DSGN's tracked universe, ranking #8 of 11. Their recent paths diverged sharply: over the last 12 months DSGN outperformed by 162.0 percentage points (+188.3% for DSGN against +26.3% for QQQ). Risk is not evenly split, since DSGN carries 3.7 times the volatility of the other side.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

DSGN vs QQQ: side by side

DSGN (Design Therapeutics, Inc.)QQQ (Invesco QQQ Trust)
1-year return+188.3%+26.3%
5-year return+0.7%+95.4%
Volatility (ann.)72.7%19.6%
Beta vs S&P 5001.351.28
Max drawdown (3Y)-62.8%-22.8%
Market cap$1.0B
P/E (trailing)
Dividend yield0.00%0.44%
Expense ratio0.18%
Assets under management$452.8B
Sector / categoryUS ListedETF · US Growth & Tech
Higher yield: QQQ 0.44% vs 0.00%Smaller drawdown: QQQ -22.8% vs -62.8%Higher 5y return: QQQ +95.4% vs +0.7%

QQQ is a Large Growth fund from Invesco: $452.8B under management, 104 holdings, a 0.18% expense ratio, a 0.44% trailing dividend yield.

-11%0%+142%2025-09-052026-08-27
Twelve months of weekly closes, each series rebased to 100. DSGN · QQQ

Year-by-year returns

YearDSGNQQQ
2022-52.1%-32.6%
2023-74.2%+54.9%
2024+132.8%+25.6%
2025+52.0%+20.8%
2026+62.6%+17.7%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are DSGN and QQQ good diversifiers for each other?

Reasonably. At 0.21, DSGN and QQQ keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.

FAQ

What is the correlation between DSGN and QQQ?

As of 2026-08-27, the correlation of weekly returns between DSGN and QQQ is 0.21 over 3 years, 0.18 over 1 year and 0.29 over 5 years.

Is QQQ a good diversifier for DSGN?

Reasonably. At 0.21, DSGN and QQQ keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.

What does a correlation of 0.21 mean?

A reading of 0.21 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.

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DSGN vs QQQ: 3-year weekly correlation 0.21DSGN vs QQQ0.21

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Hubs: DSGN correlations · QQQ correlations