AGIO vs XBI: Correlation
How closely do Agios Pharmaceuticals, Inc. (AGIO) and SPDR S&P Biotech ETF (XBI) trade together? Their weekly returns over three years give a correlation of 0.52, which is moderate.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are AGIO and XBI?
Over the past 3 years, AGIO and XBI moved with a correlation of 0.52, which is moderate. The past 12 months show a weaker link (0.42) than the 3-year average (0.52). Over 5 years the correlation is 0.59, and the annualized covariance of weekly returns is 924.1 %².
In AGIO's tracked universe of 14 assets, XBI sits right near the top at #1. Their recent paths diverged sharply: over the last 12 months XBI outperformed by 99.9 percentage points (-12.7% for AGIO against +87.2% for XBI). Risk is not evenly split, since AGIO carries 2.3 times the volatility of the other side.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
AGIO vs XBI: side by side
| AGIO (Agios Pharmaceuticals, Inc.) | XBI (SPDR S&P Biotech ETF) | |
|---|---|---|
| 1-year return | -12.7% | +87.2% |
| 5-year return | -22.1% | +28.6% |
| Volatility (ann.) | 64.3% | 27.7% |
| Beta vs S&P 500 | 1.80 | 1.09 |
| Max drawdown (3Y) | -63.8% | -33.0% |
| Market cap | $2.0B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | – |
| Sector / category | US Listed | ETF · Thematic |
Year-by-year returns
| Year | AGIO | XBI |
|---|---|---|
| 2022 | -14.6% | -25.9% |
| 2023 | -20.7% | +7.6% |
| 2024 | +47.6% | +1.0% |
| 2025 | -17.2% | +35.9% |
| 2026 | +25.9% | +38.1% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are AGIO and XBI good diversifiers for each other?
Somewhat, no more. With 0.52 correlation, most large moves hit both names, and the diversification benefit stays modest.
FAQ
What is the correlation between AGIO and XBI?
The AGIO/XBI correlation stands at 0.52 on a 3-year window (1 year: 0.42, 5 years: 0.59), computed from weekly returns as of 2026-08-27.
Is XBI a good diversifier for AGIO?
Somewhat, no more. With 0.52 correlation, most large moves hit both names, and the diversification benefit stays modest.
What does a correlation of 0.52 mean?
On the −1 to +1 scale, 0.52 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
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Related comparisons
Hubs: AGIO correlations · XBI correlations
