AGIO vs IBB: Correlation
Measured on weekly returns over the past three years, Agios Pharmaceuticals, Inc. (AGIO) and iShares Biotechnology ETF (IBB) carry a correlation of 0.48, a moderate link.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are AGIO and IBB?
Over the past 3 years, AGIO and IBB moved with a correlation of 0.48, which is moderate. The link has loosened recently: the 1-year correlation (0.35) runs below the 3-year figure (0.48). Over 5 years the correlation is 0.53, and the annualized covariance of weekly returns is 644.8 %².
Within AGIO's tracked universe of 14 assets, IBB comes in at #4 by 3-year correlation. The last year tells two different stories: IBB led by 68.1 percentage points, -12.7% for AGIO against +55.4% for IBB. One caveat on sizing: AGIO is 3.1 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
AGIO vs IBB: side by side
| AGIO (Agios Pharmaceuticals, Inc.) | IBB (iShares Biotechnology ETF) | |
|---|---|---|
| 1-year return | -12.7% | +55.4% |
| 5-year return | -22.1% | +26.6% |
| Volatility (ann.) | 64.3% | 20.7% |
| Beta vs S&P 500 | 1.80 | 0.81 |
| Max drawdown (3Y) | -63.8% | -24.9% |
| Market cap | $2.0B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.22% |
| Expense ratio | – | 0.44% |
| Assets under management | – | $9.2B |
| Sector / category | US Listed | ETF · Thematic |
IBB, iShares's Health fund, carries $9.2B under management, 235 holdings, a 0.44% expense ratio, a 0.22% trailing dividend yield.
Year-by-year returns
| Year | AGIO | IBB |
|---|---|---|
| 2022 | -14.6% | -13.7% |
| 2023 | -20.7% | +3.8% |
| 2024 | +47.6% | -2.4% |
| 2025 | -17.2% | +28.0% |
| 2026 | +25.9% | +27.4% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Fund exposure
Keep in mind that IBB holds AGIO at a 0.13% weight, which makes a slice of this correlation mechanical rather than coincidental.
Are AGIO and IBB good diversifiers for each other?
Yes, to a useful degree: a correlation of 0.48 leaves real independence between the two, which historically damped combined volatility.
FAQ
What is the correlation between AGIO and IBB?
The AGIO/IBB correlation stands at 0.48 on a 3-year window (1 year: 0.35, 5 years: 0.53), computed from weekly returns as of 2026-08-27.
Is IBB a good diversifier for AGIO?
Yes, to a useful degree: a correlation of 0.48 leaves real independence between the two, which historically damped combined volatility.
What does a correlation of 0.48 mean?
A reading of 0.48 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/agio-vs-ibb.json
Embed this badge (it refreshes with the data), with attribution:
[](https://www.pairbook.io/pair/agio-vs-ibb/)
No key needed, free to use. Full endpoint list in the API documentation.
Related comparisons
Hubs: AGIO correlations · IBB correlations
