SPY vs VTVT: Correlation
SPDR S&P 500 ETF Trust (SPY) and vTv Therapeutics Inc. (VTVT) show a near-zero relationship: their 3-year correlation of weekly returns is 0.09.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are SPY and VTVT?
On 3 years of weekly data the SPY/VTVT correlation comes out at 0.09, near zero, meaning they move largely independently. The link has loosened recently: the 1-year correlation (-0.09) runs below the 3-year figure (0.09). The 5-year figure is 0.18, and annualized covariance runs at 134.5 %².
Among the 4755 assets we track against SPY, VTVT ranks #4182 by 3-year correlation. The last year tells two different stories: VTVT led by 81.4 percentage points, +20.6% for SPY against +102.0% for VTVT. Note the risk asymmetry: VTVT runs 6.9 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
SPY vs VTVT: side by side
| SPY (SPDR S&P 500 ETF Trust) | VTVT (vTv Therapeutics Inc.) | |
|---|---|---|
| 1-year return | +20.6% | +102.0% |
| 5-year return | +82.4% | -56.6% |
| Volatility (ann.) | 14.5% | 100.1% |
| Beta vs S&P 500 | 1.00 | 0.64 |
| Max drawdown (3Y) | -18.8% | -61.7% |
| Market cap | – | $0.1B |
| P/E (trailing) | – | – |
| Dividend yield | 1.01% | 0.00% |
| Expense ratio | 0.09% | – |
| Assets under management | $795.3B | – |
| Sector / category | ETF · US Large Cap | US Listed |
SPY is a Large Blend fund from State Street Investment Management: $795.3B under management, 504 holdings, a 0.09% expense ratio, a 1.01% trailing dividend yield.
Year-by-year returns
| Year | SPY | VTVT |
|---|---|---|
| 2022 | -18.2% | -33.4% |
| 2023 | +26.2% | -56.6% |
| 2024 | +24.9% | +20.1% |
| 2025 | +17.7% | +189.6% |
| 2026 | +13.7% | -18.0% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are SPY and VTVT good diversifiers for each other?
Yes: at 0.09, the two have gone their own ways historically, which is what genuine diversification looks like.
FAQ
What is the correlation between SPY and VTVT?
As of 2026-08-27, the correlation of weekly returns between SPY and VTVT is 0.09 over 3 years, -0.09 over 1 year and 0.18 over 5 years.
Is VTVT a good diversifier for SPY?
Yes: at 0.09, the two have gone their own ways historically, which is what genuine diversification looks like.
What does a correlation of 0.09 mean?
On the −1 to +1 scale, 0.09 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/spy-vs-vtvt.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/spy-vs-vtvt/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: SPY correlations · VTVT correlations
