SPY vs TXG: Correlation
SPDR S&P 500 ETF Trust (SPY) and 10x Genomics, Inc. (TXG) show a moderate relationship: their 3-year correlation of weekly returns is 0.35.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are SPY and TXG?
Over the past 3 years, SPY and TXG moved with a correlation of 0.35, which is moderate. Lately the two have drifted apart, with the 1-year correlation at 0.21 versus 0.35 over 3 years. Over 5 years the correlation is 0.49, and the annualized covariance of weekly returns is 324.1 %².
Among the 4755 assets we track against SPY, TXG ranks #1708 by 3-year correlation. The last year tells two different stories: TXG led by 342.0 percentage points, +20.6% for SPY against +362.6% for TXG. One caveat on sizing: TXG is 4.4 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
SPY vs TXG: side by side
| SPY (SPDR S&P 500 ETF Trust) | TXG (10x Genomics, Inc.) | |
|---|---|---|
| 1-year return | +20.6% | +362.6% |
| 5-year return | +82.4% | -62.7% |
| Volatility (ann.) | 14.5% | 64.3% |
| Beta vs S&P 500 | 1.00 | 1.55 |
| Max drawdown (3Y) | -18.8% | -87.6% |
| Market cap | – | $8.4B |
| P/E (trailing) | – | – |
| Dividend yield | 1.01% | 0.00% |
| Expense ratio | 0.09% | – |
| Assets under management | $795.3B | – |
| Sector / category | ETF · US Large Cap | US Listed |
SPY is a Large Blend fund from State Street Investment Management: $795.3B under management, 504 holdings, a 0.09% expense ratio, a 1.01% trailing dividend yield.
Year-by-year returns
| Year | SPY | TXG |
|---|---|---|
| 2022 | -18.2% | -75.5% |
| 2023 | +26.2% | +53.6% |
| 2024 | +24.9% | -74.3% |
| 2025 | +17.7% | +13.6% |
| 2026 | +13.7% | +297.6% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are SPY and TXG good diversifiers for each other?
A fair diversifier. At 0.35, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
FAQ
What is the correlation between SPY and TXG?
The SPY/TXG correlation stands at 0.35 on a 3-year window (1 year: 0.21, 5 years: 0.49), computed from weekly returns as of 2026-08-27.
Is TXG a good diversifier for SPY?
A fair diversifier. At 0.35, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
What does a correlation of 0.35 mean?
A reading of 0.35 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/spy-vs-txg.json
Markdown for the live badge, attribution link included:
[](https://www.pairbook.io/pair/spy-vs-txg/)
Free with attribution; caching and terms are described in the API documentation.
Related comparisons
Hubs: SPY correlations · TXG correlations
