SPY vs TSHA: Correlation
SPDR S&P 500 ETF Trust (SPY) and Taysha Gene Therapies, Inc. (TSHA) show a moderate relationship: their 3-year correlation of weekly returns is 0.38.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are SPY and TSHA?
On 3 years of weekly data the SPY/TSHA correlation comes out at 0.38, moderate. Little has changed lately, as the 1-year reading of 0.43 lands near the 3-year figure. The 5-year figure is 0.27, and annualized covariance runs at 550.2 %².
By 3-year correlation, TSHA places #1400 of the 4755 assets tracked against SPY. Correlation aside, the last 12 months split them widely, with TSHA ahead by 80.1 points (+20.6% versus +100.7%). Risk is not evenly split, since TSHA carries 7.0 times the volatility of the other side.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
SPY vs TSHA: side by side
| SPY (SPDR S&P 500 ETF Trust) | TSHA (Taysha Gene Therapies, Inc.) | |
|---|---|---|
| 1-year return | +20.6% | +100.7% |
| 5-year return | +82.4% | -69.5% |
| Volatility (ann.) | 14.5% | 101.5% |
| Beta vs S&P 500 | 1.00 | 2.63 |
| Max drawdown (3Y) | -18.8% | -72.9% |
| Market cap | – | $1.9B |
| P/E (trailing) | – | – |
| Dividend yield | 1.01% | 0.00% |
| Expense ratio | 0.09% | – |
| Assets under management | $795.3B | – |
| Sector / category | ETF · US Large Cap | US Listed |
On the fund side, SPY sits in the Large Blend category at State Street Investment Management, with $795.3B under management, 504 holdings, a 0.09% expense ratio, a 1.01% trailing dividend yield.
Year-by-year returns
| Year | SPY | TSHA |
|---|---|---|
| 2022 | -18.2% | -80.6% |
| 2023 | +26.2% | -21.7% |
| 2024 | +24.9% | -2.3% |
| 2025 | +17.7% | +217.9% |
| 2026 | +13.7% | +8.4% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are SPY and TSHA good diversifiers for each other?
A fair diversifier. At 0.38, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
FAQ
What is the correlation between SPY and TSHA?
The SPY/TSHA correlation stands at 0.38 on a 3-year window (1 year: 0.43, 5 years: 0.27), computed from weekly returns as of 2026-08-27.
Is TSHA a good diversifier for SPY?
A fair diversifier. At 0.38, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
What does a correlation of 0.38 mean?
On the −1 to +1 scale, 0.38 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/spy-vs-tsha.json
Markdown for the live badge, attribution link included:
[](https://www.pairbook.io/pair/spy-vs-tsha/)
No key needed, free to use. Full endpoint list in the API documentation.
Related comparisons
Hubs: SPY correlations · TSHA correlations
