NRSN vs SYRE: Correlation
NeuroSense Therapeutics Ltd. (NRSN) and Spyre Therapeutics, Inc. (SYRE) show a moderate relationship: their 3-year correlation of weekly returns is 0.34.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are NRSN and SYRE?
Over the past 3 years, NRSN and SYRE moved with a correlation of 0.34, which is moderate. The past 12 months show a weaker link (0.01) than the 3-year average (0.34). Over 5 years the correlation is 0.06, and the annualized covariance of weekly returns is 3337.8 %².
By 3-year correlation, SYRE places #4 of the 10 assets tracked against NRSN. Correlation aside, the last 12 months split them widely, with SYRE ahead by 507.0 points (-60.8% versus +446.2%).
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
NRSN vs SYRE: side by side
| NRSN (NeuroSense Therapeutics Ltd.) | SYRE (Spyre Therapeutics, Inc.) | |
|---|---|---|
| 1-year return | -60.8% | +446.2% |
| 5-year return | -89.1% | -47.5% |
| Volatility (ann.) | 118.6% | 83.8% |
| Beta vs S&P 500 | 1.68 | 1.80 |
| Max drawdown (3Y) | -85.9% | -74.0% |
| Market cap | – | $8.3B |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | NRSN | SYRE |
|---|---|---|
| 2022 | -50.4% | -90.5% |
| 2023 | -35.7% | +91.3% |
| 2024 | +52.9% | +8.2% |
| 2025 | -35.9% | +40.7% |
| 2026 | -42.9% | +185.8% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are NRSN and SYRE good diversifiers for each other?
Yes, to a useful degree: a correlation of 0.34 leaves real independence between the two, which historically damped combined volatility.
FAQ
What is the correlation between NRSN and SYRE?
Using weekly returns as of 2026-08-27: 0.34 over 3 years, with 0.01 over the last year and 0.06 over 5 years.
Is SYRE a good diversifier for NRSN?
Yes, to a useful degree: a correlation of 0.34 leaves real independence between the two, which historically damped combined volatility.
What does a correlation of 0.34 mean?
On the −1 to +1 scale, 0.34 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/nrsn-vs-syre.json
Embed this badge (it refreshes with the data), with attribution:
[](https://www.pairbook.io/pair/nrsn-vs-syre/)
No key needed, free to use. Full endpoint list in the API documentation.
Related comparisons
Hubs: NRSN correlations · SYRE correlations
