MIST vs VXZ: Correlation
Measured on weekly returns over the past three years, Milestone Pharmaceuticals Inc. (MIST) and iPath Series B S&P 500 VIX Mid-Term Futures ETN (VXZ) carry a correlation of -0.33, a negative link.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are MIST and VXZ?
Over the past 3 years, MIST and VXZ moved with a correlation of -0.33, which is negative, meaning they tend to move in opposite directions. The link has loosened recently: the 1-year correlation (-0.45) runs below the 3-year figure (-0.33). Over 5 years the correlation is -0.25, and the annualized covariance of weekly returns is -759.9 %².
Out of 11 assets tracked against MIST, VXZ lands near the bottom at #9. Their recent paths diverged sharply: over the last 12 months VXZ outperformed by 16.7 percentage points (-32.8% for MIST against -16.1% for VXZ). Note the risk asymmetry: MIST runs 3.6 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
MIST vs VXZ: side by side
| MIST (Milestone Pharmaceuticals Inc.) | VXZ (iPath Series B S&P 500 VIX Mid-Term Futures ETN) | |
|---|---|---|
| 1-year return | -32.8% | -16.1% |
| 5-year return | -80.4% | -53.1% |
| Volatility (ann.) | 91.2% | 25.6% |
| Beta vs S&P 500 | 2.57 | -1.31 |
| Max drawdown (3Y) | -80.7% | -36.4% |
| Market cap | $0.1B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | – |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | MIST | VXZ |
|---|---|---|
| 2022 | -39.5% | +0.5% |
| 2023 | -57.8% | -44.0% |
| 2024 | +41.3% | -12.7% |
| 2025 | -14.4% | +5.7% |
| 2026 | -41.1% | -10.5% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are MIST and VXZ good diversifiers for each other?
Yes: at -0.33, the two have gone their own ways historically, which is what genuine diversification looks like.
FAQ
What is the correlation between MIST and VXZ?
The MIST/VXZ correlation stands at -0.33 on a 3-year window (1 year: -0.45, 5 years: -0.25), computed from weekly returns as of 2026-08-27.
Is VXZ a good diversifier for MIST?
Yes: at -0.33, the two have gone their own ways historically, which is what genuine diversification looks like.
What does a correlation of -0.33 mean?
A reading of -0.33 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/mist-vs-vxz.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/mist-vs-vxz/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: MIST correlations · VXZ correlations
