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MIST vs VT: Correlation

How closely do Milestone Pharmaceuticals Inc. (MIST) and Vanguard Total World Stock ETF (VT) trade together? Their weekly returns over three years give a correlation of 0.43, which is moderate.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.43
moderate
Correlation (1Y)
0.54
last 12 months
Correlation (5Y)
0.31
long-run
Ann. covariance
550.0
%² · weekly, annualized

How correlated are MIST and VT?

On 3 years of weekly data the MIST/VT correlation comes out at 0.43, moderate. Lately the two have moved closer together, with the 1-year correlation at 0.54 versus 0.43 over 3 years. The 5-year figure is 0.31, and annualized covariance runs at 550.0 %².

By 3-year correlation, VT places #5 of the 11 assets tracked against MIST. Their recent paths diverged sharply: over the last 12 months VT outperformed by 55.5 percentage points (-32.8% for MIST against +22.7% for VT). Note the risk asymmetry: MIST runs 6.6 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

MIST vs VT: side by side

MIST (Milestone Pharmaceuticals Inc.)VT (Vanguard Total World Stock ETF)
1-year return-32.8%+22.7%
5-year return-80.4%+67.7%
Volatility (ann.)91.2%13.9%
Beta vs S&P 5002.570.92
Max drawdown (3Y)-80.7%-16.5%
Market cap$0.1B
P/E (trailing)
Dividend yield0.00%1.59%
Expense ratio0.06%
Assets under management$97.9B
Sector / categoryUS ListedETF · Global
Higher yield: VT 1.59% vs 0.00%Smaller drawdown: VT -16.5% vs -80.7%Higher 5y return: VT +67.7% vs -80.4%

VT is a Global Large-Stock Blend fund from Vanguard: $97.9B under management, 5308 holdings, a 0.06% expense ratio, a 1.59% trailing dividend yield.

-42%0%+49%2025-09-052026-08-27
Price paths over the last 12 months, both indexed to 100 at the start (weekly closes). MIST · VT

Year-by-year returns

YearMISTVT
2022-39.5%-18.0%
2023-57.8%+22.0%
2024+41.3%+16.5%
2025-14.4%+22.4%
2026-41.1%+15.2%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are MIST and VT good diversifiers for each other?

Reasonably. At 0.43, MIST and VT keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.

FAQ

What is the correlation between MIST and VT?

Using weekly returns as of 2026-08-27: 0.43 over 3 years, with 0.54 over the last year and 0.31 over 5 years.

Is VT a good diversifier for MIST?

Reasonably. At 0.43, MIST and VT keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.

What does a correlation of 0.43 mean?

On the −1 to +1 scale, 0.43 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.

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MIST vs VT: 3-year weekly correlation 0.43MIST vs VT0.43

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Related comparisons

Hubs: MIST correlations · VT correlations