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MIST vs VXX: Correlation

How closely do Milestone Pharmaceuticals Inc. (MIST) and iPath Series B S&P 500 VIX Short-Term Futures ETN (VXX) trade together? Their weekly returns over three years give a correlation of -0.34, which is negative.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
-0.34
negative
Correlation (1Y)
-0.43
last 12 months
Correlation (5Y)
-0.27
long-run
Ann. covariance
-1888.5
%² · weekly, annualized

How correlated are MIST and VXX?

Over the past 3 years, MIST and VXX moved with a correlation of -0.34, which is negative, meaning they tend to move in opposite directions. The relationship has been stable: the 1-year correlation (-0.43) sits close to the 3-year figure. Over 5 years the correlation is -0.27, and the annualized covariance of weekly returns is -1888.5 %².

Out of 11 assets tracked against MIST, VXX lands near the bottom at #10. The last year tells two different stories: MIST led by 16.9 percentage points, -32.8% for MIST against -49.7% for VXX.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

MIST vs VXX: side by side

MIST (Milestone Pharmaceuticals Inc.)VXX (iPath Series B S&P 500 VIX Short-Term Futures ETN)
1-year return-32.8%-49.7%
5-year return-80.4%-95.6%
Volatility (ann.)91.2%60.9%
Beta vs S&P 5002.57-3.31
Max drawdown (3Y)-80.7%-83.3%
Market cap$0.1B
P/E (trailing)
Dividend yield0.00%0.00%
Sector / categoryUS ListedUS Listed
Smaller drawdown: MIST -80.7% vs -83.3%Higher 5y return: MIST -80.4% vs -95.6%
-49%0%+49%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. MIST · VXX

Year-by-year returns

YearMISTVXX
2022-39.5%-23.8%
2023-57.8%-72.5%
2024+41.3%-26.2%
2025-14.4%-42.2%
2026-41.1%-31.6%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are MIST and VXX good diversifiers for each other?

By historical standards, yes. A correlation of -0.34 means the two rarely move for the same reasons.

FAQ

What is the correlation between MIST and VXX?

Using weekly returns as of 2026-08-27: -0.34 over 3 years, with -0.43 over the last year and -0.27 over 5 years.

Is VXX a good diversifier for MIST?

By historical standards, yes. A correlation of -0.34 means the two rarely move for the same reasons.

What does a correlation of -0.34 mean?

On the −1 to +1 scale, -0.34 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.

Use this data

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MIST vs VXX: 3-year weekly correlation -0.34MIST vs VXX-0.34

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Hubs: MIST correlations · VXX correlations