PairBook
HomeCSTL › CSTL vs MYGN

CSTL vs MYGN: Correlation

How closely do Castle Biosciences, Inc. (CSTL) and Myriad Genetics, Inc. (MYGN) trade together? Their weekly returns over three years give a correlation of 0.43, which is moderate.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.43
moderate
Correlation (1Y)
0.11
last 12 months
Correlation (5Y)
0.38
long-run
Ann. covariance
2200.0
%² · weekly, annualized

How correlated are CSTL and MYGN?

Across a 3-year window, the weekly returns of CSTL and MYGN correlate at 0.43, moderate. Lately the two have drifted apart, with the 1-year correlation at 0.11 versus 0.43 over 3 years. Stretching to 5 years gives 0.38, with an annualized covariance of 2200.0 %².

By 3-year correlation, MYGN places #6 of the 12 assets tracked against CSTL. The last year tells two different stories: CSTL led by 100.2 percentage points, +53.8% for CSTL against -46.4% for MYGN.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

CSTL vs MYGN: side by side

CSTL (Castle Biosciences, Inc.)MYGN (Myriad Genetics, Inc.)
1-year return+53.8%-46.4%
5-year return-54.0%-91.1%
Volatility (ann.)64.2%80.5%
Beta vs S&P 5000.791.49
Max drawdown (3Y)-57.8%-90.0%
Market cap$1.0B$0.3B
P/E (trailing)
Dividend yield0.00%0.00%
Sector / categoryUS ListedUS Listed
Smaller drawdown: CSTL -57.8% vs -90.0%Higher 5y return: CSTL -54.0% vs -91.1%
-57%0%+79%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. CSTL · MYGN

Year-by-year returns

YearCSTLMYGN
2022-45.1%-47.4%
2023-8.3%+31.9%
2024+23.5%-28.4%
2025+46.0%-55.1%
2026-11.9%-48.3%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are CSTL and MYGN good diversifiers for each other?

Reasonably. At 0.43, CSTL and MYGN keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.

FAQ

What is the correlation between CSTL and MYGN?

The CSTL/MYGN correlation stands at 0.43 on a 3-year window (1 year: 0.11, 5 years: 0.38), computed from weekly returns as of 2026-08-27.

Is MYGN a good diversifier for CSTL?

Reasonably. At 0.43, CSTL and MYGN keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.

What does a correlation of 0.43 mean?

Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.

Use this data

JSON API · no key required
$ curl https://www.pairbook.io/api/v1/pairs/cstl-vs-mygn.json

CSTL vs MYGN: 3-year weekly correlation 0.43CSTL vs MYGN0.43

Embed this badge (it refreshes with the data), with attribution:

[![CSTL vs MYGN correlation](https://www.pairbook.io/api/v1/badge/cstl-vs-mygn.svg)](https://www.pairbook.io/pair/cstl-vs-mygn/)

No key needed, free to use. Full endpoint list in the API documentation.

Related comparisons

Hubs: CSTL correlations · MYGN correlations