CSTL vs MYGN: Correlation
How closely do Castle Biosciences, Inc. (CSTL) and Myriad Genetics, Inc. (MYGN) trade together? Their weekly returns over three years give a correlation of 0.43, which is moderate.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are CSTL and MYGN?
Across a 3-year window, the weekly returns of CSTL and MYGN correlate at 0.43, moderate. Lately the two have drifted apart, with the 1-year correlation at 0.11 versus 0.43 over 3 years. Stretching to 5 years gives 0.38, with an annualized covariance of 2200.0 %².
By 3-year correlation, MYGN places #6 of the 12 assets tracked against CSTL. The last year tells two different stories: CSTL led by 100.2 percentage points, +53.8% for CSTL against -46.4% for MYGN.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
CSTL vs MYGN: side by side
| CSTL (Castle Biosciences, Inc.) | MYGN (Myriad Genetics, Inc.) | |
|---|---|---|
| 1-year return | +53.8% | -46.4% |
| 5-year return | -54.0% | -91.1% |
| Volatility (ann.) | 64.2% | 80.5% |
| Beta vs S&P 500 | 0.79 | 1.49 |
| Max drawdown (3Y) | -57.8% | -90.0% |
| Market cap | $1.0B | $0.3B |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | CSTL | MYGN |
|---|---|---|
| 2022 | -45.1% | -47.4% |
| 2023 | -8.3% | +31.9% |
| 2024 | +23.5% | -28.4% |
| 2025 | +46.0% | -55.1% |
| 2026 | -11.9% | -48.3% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are CSTL and MYGN good diversifiers for each other?
Reasonably. At 0.43, CSTL and MYGN keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
FAQ
What is the correlation between CSTL and MYGN?
The CSTL/MYGN correlation stands at 0.43 on a 3-year window (1 year: 0.11, 5 years: 0.38), computed from weekly returns as of 2026-08-27.
Is MYGN a good diversifier for CSTL?
Reasonably. At 0.43, CSTL and MYGN keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
What does a correlation of 0.43 mean?
Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/cstl-vs-mygn.json
Embed this badge (it refreshes with the data), with attribution:
[](https://www.pairbook.io/pair/cstl-vs-mygn/)
No key needed, free to use. Full endpoint list in the API documentation.
Related comparisons
Hubs: CSTL correlations · MYGN correlations