CSTL vs VXZ: Correlation
Measured on weekly returns over the past three years, Castle Biosciences, Inc. (CSTL) and iPath Series B S&P 500 VIX Mid-Term Futures ETN (VXZ) carry a correlation of -0.22, a negative link.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are CSTL and VXZ?
Over the past 3 years, CSTL and VXZ moved with a correlation of -0.22, which is negative, meaning they tend to move in opposite directions. Little has changed lately, as the 1-year reading of -0.16 lands near the 3-year figure. Over 5 years the correlation is -0.22, and the annualized covariance of weekly returns is -364.7 %².
Out of 12 assets tracked against CSTL, VXZ lands near the bottom at #12. Their recent paths diverged sharply: over the last 12 months CSTL outperformed by 69.9 percentage points (+53.8% for CSTL against -16.1% for VXZ). Note the risk asymmetry: CSTL runs 2.5 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
CSTL vs VXZ: side by side
| CSTL (Castle Biosciences, Inc.) | VXZ (iPath Series B S&P 500 VIX Mid-Term Futures ETN) | |
|---|---|---|
| 1-year return | +53.8% | -16.1% |
| 5-year return | -54.0% | -53.1% |
| Volatility (ann.) | 64.2% | 25.6% |
| Beta vs S&P 500 | 0.79 | -1.31 |
| Max drawdown (3Y) | -57.8% | -36.4% |
| Market cap | $1.0B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | – |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | CSTL | VXZ |
|---|---|---|
| 2022 | -45.1% | +0.5% |
| 2023 | -8.3% | -44.0% |
| 2024 | +23.5% | -12.7% |
| 2025 | +46.0% | +5.7% |
| 2026 | -11.9% | -10.5% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are CSTL and VXZ good diversifiers for each other?
Yes. With a correlation of -0.22, CSTL and VXZ have moved largely independently, which makes them a genuinely diversifying pair by historical standards.
FAQ
What is the correlation between CSTL and VXZ?
The CSTL/VXZ correlation stands at -0.22 on a 3-year window (1 year: -0.16, 5 years: -0.22), computed from weekly returns as of 2026-08-27.
Is VXZ a good diversifier for CSTL?
Yes. With a correlation of -0.22, CSTL and VXZ have moved largely independently, which makes them a genuinely diversifying pair by historical standards.
What does a correlation of -0.22 mean?
Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/cstl-vs-vxz.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/cstl-vs-vxz/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: CSTL correlations · VXZ correlations
