CMPX vs XBI: Correlation
How closely do Compass Therapeutics, Inc. (CMPX) and SPDR S&P Biotech ETF (XBI) trade together? Their weekly returns over three years give a correlation of 0.45, which is moderate.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are CMPX and XBI?
On 3 years of weekly data the CMPX/XBI correlation comes out at 0.45, moderate. Little has changed lately, as the 1-year reading of 0.39 lands near the 3-year figure. The 5-year figure is 0.37, and annualized covariance runs at 1069.9 %².
XBI is one of the assets that tracks CMPX most closely: it ranks #2 out of the 10 assets we track against CMPX. Their recent paths diverged sharply: over the last 12 months XBI outperformed by 110.4 percentage points (-23.2% for CMPX against +87.2% for XBI). One caveat on sizing: CMPX is 3.1 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
CMPX vs XBI: side by side
| CMPX (Compass Therapeutics, Inc.) | XBI (SPDR S&P Biotech ETF) | |
|---|---|---|
| 1-year return | -23.2% | +87.2% |
| 5-year return | -37.8% | +28.6% |
| Volatility (ann.) | 85.8% | 27.7% |
| Beta vs S&P 500 | 1.92 | 1.09 |
| Max drawdown (3Y) | -75.0% | -33.0% |
| Market cap | $0.5B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | – |
| Sector / category | US Listed | ETF · Thematic |
Year-by-year returns
| Year | CMPX | XBI |
|---|---|---|
| 2022 | +58.7% | -25.9% |
| 2023 | -69.0% | +7.6% |
| 2024 | -7.1% | +1.0% |
| 2025 | +270.3% | +35.9% |
| 2026 | -53.1% | +38.1% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are CMPX and XBI good diversifiers for each other?
A fair diversifier. At 0.45, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
FAQ
What is the correlation between CMPX and XBI?
The CMPX/XBI correlation stands at 0.45 on a 3-year window (1 year: 0.39, 5 years: 0.37), computed from weekly returns as of 2026-08-27.
Is XBI a good diversifier for CMPX?
A fair diversifier. At 0.45, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
What does a correlation of 0.45 mean?
On the −1 to +1 scale, 0.45 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/cmpx-vs-xbi.json
Embed this badge (it refreshes with the data), with attribution:
[](https://www.pairbook.io/pair/cmpx-vs-xbi/)
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Related comparisons
Hubs: CMPX correlations · XBI correlations
