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CMPX vs DNLI: Correlation

How closely do Compass Therapeutics, Inc. (CMPX) and Denali Therapeutics Inc. (DNLI) trade together? Their weekly returns over three years give a correlation of 0.43, which is moderate.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.43
moderate
Correlation (1Y)
0.42
last 12 months
Correlation (5Y)
0.38
long-run
Ann. covariance
2258.8
%² · weekly, annualized

How correlated are CMPX and DNLI?

On 3 years of weekly data the CMPX/DNLI correlation comes out at 0.43, moderate. The relationship has been stable: the 1-year correlation (0.42) sits close to the 3-year figure. The 5-year figure is 0.38, and annualized covariance runs at 2258.8 %².

By 3-year correlation, DNLI places #4 of the 10 assets tracked against CMPX. The last year tells two different stories: DNLI led by 81.3 percentage points, -23.2% for CMPX against +58.1% for DNLI.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

CMPX vs DNLI: side by side

CMPX (Compass Therapeutics, Inc.)DNLI (Denali Therapeutics Inc.)
1-year return-23.2%+58.1%
5-year return-37.8%-53.4%
Volatility (ann.)85.8%60.6%
Beta vs S&P 5001.922.02
Max drawdown (3Y)-75.0%-63.7%
Market cap$0.5B$3.9B
P/E (trailing)
Dividend yield0.00%0.00%
Sector / categoryUS ListedUS Listed
Smaller drawdown: DNLI -63.7% vs -75.0%Higher 5y return: CMPX -37.8% vs -53.4%
-47%0%+90%2025-09-052026-08-27
Price paths over the last 12 months, both indexed to 100 at the start (weekly closes). CMPX · DNLI

Year-by-year returns

YearCMPXDNLI
2022+58.7%-37.6%
2023-69.0%-22.8%
2024-7.1%-5.0%
2025+270.3%-19.0%
2026-53.1%+49.4%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are CMPX and DNLI good diversifiers for each other?

Reasonably. At 0.43, CMPX and DNLI keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.

FAQ

What is the correlation between CMPX and DNLI?

Using weekly returns as of 2026-08-27: 0.43 over 3 years, with 0.42 over the last year and 0.38 over 5 years.

Is DNLI a good diversifier for CMPX?

Reasonably. At 0.43, CMPX and DNLI keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.

What does a correlation of 0.43 mean?

On the −1 to +1 scale, 0.43 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.

Use this data

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$ curl https://www.pairbook.io/api/v1/pairs/cmpx-vs-dnli.json

CMPX vs DNLI: 3-year weekly correlation 0.43CMPX vs DNLI0.43

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Related comparisons

Hubs: CMPX correlations · DNLI correlations