CMPX vs SPY: Correlation
Compass Therapeutics, Inc. (CMPX) and SPDR S&P 500 ETF Trust (SPY) show a moderate relationship: their 3-year correlation of weekly returns is 0.32.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are CMPX and SPY?
Across a 3-year window, the weekly returns of CMPX and SPY correlate at 0.32, moderate. The link has loosened recently: the 1-year correlation (0.14) runs below the 3-year figure (0.32). Stretching to 5 years gives 0.25, with an annualized covariance of 400.8 %².
Out of 10 assets tracked against CMPX, SPY lands near the bottom at #6. Correlation aside, the last 12 months split them widely, with SPY ahead by 43.8 points (-23.2% versus +20.6%). Note the risk asymmetry: CMPX runs 5.9 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
CMPX vs SPY: side by side
| CMPX (Compass Therapeutics, Inc.) | SPY (SPDR S&P 500 ETF Trust) | |
|---|---|---|
| 1-year return | -23.2% | +20.6% |
| 5-year return | -37.8% | +82.4% |
| Volatility (ann.) | 85.8% | 14.5% |
| Beta vs S&P 500 | 1.92 | 1.00 |
| Max drawdown (3Y) | -75.0% | -18.8% |
| Market cap | $0.5B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 1.01% |
| Expense ratio | – | 0.09% |
| Assets under management | – | $795.3B |
| Sector / category | US Listed | ETF · US Large Cap |
SPY is a Large Blend fund from State Street Investment Management: $795.3B under management, 504 holdings, a 0.09% expense ratio, a 1.01% trailing dividend yield.
Year-by-year returns
| Year | CMPX | SPY |
|---|---|---|
| 2022 | +58.7% | -18.2% |
| 2023 | -69.0% | +26.2% |
| 2024 | -7.1% | +24.9% |
| 2025 | +270.3% | +17.7% |
| 2026 | -53.1% | +13.7% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are CMPX and SPY good diversifiers for each other?
Reasonably. At 0.32, CMPX and SPY keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
FAQ
What is the correlation between CMPX and SPY?
The CMPX/SPY correlation stands at 0.32 on a 3-year window (1 year: 0.14, 5 years: 0.25), computed from weekly returns as of 2026-08-27.
Is SPY a good diversifier for CMPX?
Reasonably. At 0.32, CMPX and SPY keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
What does a correlation of 0.32 mean?
Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.
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Related comparisons
Hubs: CMPX correlations · SPY correlations
