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CBIO vs GLUE: Correlation

How closely do Crescent Biopharma, Inc. (CBIO) and Monte Rosa Therapeutics, Inc. (GLUE) trade together? Their weekly returns over three years give a correlation of 0.49, which is moderate.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.49
moderate
Correlation (1Y)
0.15
last 12 months
Correlation (5Y)
0.32
long-run
Ann. covariance
6006.4
%² · weekly, annualized

How correlated are CBIO and GLUE?

On 3 years of weekly data the CBIO/GLUE correlation comes out at 0.49, moderate. Lately the two have drifted apart, with the 1-year correlation at 0.15 versus 0.49 over 3 years. The 5-year figure is 0.32, and annualized covariance runs at 6006.4 %².

Few assets follow CBIO as closely as GLUE, which ranks #2 of 16 tracked partners. Correlation aside, the last 12 months split them widely, with GLUE ahead by 182.0 points (+24.6% versus +206.6%).

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

CBIO vs GLUE: side by side

CBIO (Crescent Biopharma, Inc.)GLUE (Monte Rosa Therapeutics, Inc.)
1-year return+24.6%+206.6%
5-year return-107.8%-61.7%
Volatility (ann.)117.9%104.5%
Beta vs S&P 5001.301.91
Max drawdown (3Y)-97.4%-64.3%
Market cap$0.7B$1.2B
P/E (trailing)
Dividend yield0.00%0.00%
Sector / categoryUS ListedUS Listed
Smaller drawdown: GLUE -64.3% vs -97.4%Higher 5y return: GLUE -61.7% vs -107.8%
-37%0%+397%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. CBIO · GLUE

Year-by-year returns

YearCBIOGLUE
2022-275.3%-62.7%
2023-15.0%-25.8%
2024-89.4%+22.8%
2025-52.6%+125.9%
2026+49.7%-8.7%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are CBIO and GLUE good diversifiers for each other?

Yes, to a useful degree: a correlation of 0.49 leaves real independence between the two, which historically damped combined volatility.

FAQ

What is the correlation between CBIO and GLUE?

The CBIO/GLUE correlation stands at 0.49 on a 3-year window (1 year: 0.15, 5 years: 0.32), computed from weekly returns as of 2026-08-27.

Is GLUE a good diversifier for CBIO?

Yes, to a useful degree: a correlation of 0.49 leaves real independence between the two, which historically damped combined volatility.

What does a correlation of 0.49 mean?

On the −1 to +1 scale, 0.49 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.

Use this data

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CBIO vs GLUE: 3-year weekly correlation 0.49CBIO vs GLUE0.49

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Related comparisons

Hubs: CBIO correlations · GLUE correlations