CBIO vs ENSC: Correlation
How closely do Crescent Biopharma, Inc. (CBIO) and Ensysce Biosciences, Inc. (ENSC) trade together? Their weekly returns over three years give a correlation of 0.39, which is moderate.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are CBIO and ENSC?
Across a 3-year window, the weekly returns of CBIO and ENSC correlate at 0.39, moderate. Lately the two have drifted apart, with the 1-year correlation at 0.18 versus 0.39 over 3 years. Stretching to 5 years gives 0.21, with an annualized covariance of 6830.6 %².
Within CBIO's tracked universe of 16 assets, ENSC comes in at #8 by 3-year correlation. Their recent paths diverged sharply: over the last 12 months CBIO outperformed by 105.4 percentage points (+24.6% for CBIO against -80.8% for ENSC).
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
CBIO vs ENSC: side by side
| CBIO (Crescent Biopharma, Inc.) | ENSC (Ensysce Biosciences, Inc.) | |
|---|---|---|
| 1-year return | +24.6% | -80.8% |
| 5-year return | -107.8% | -100.0% |
| Volatility (ann.) | 117.9% | 150.3% |
| Beta vs S&P 500 | 1.30 | 2.11 |
| Max drawdown (3Y) | -97.4% | -99.1% |
| Market cap | $0.7B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | CBIO | ENSC |
|---|---|---|
| 2022 | -275.3% | -99.2% |
| 2023 | -15.0% | -88.2% |
| 2024 | -89.4% | -48.8% |
| 2025 | -52.6% | -88.7% |
| 2026 | +49.7% | -56.6% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are CBIO and ENSC good diversifiers for each other?
A fair diversifier. At 0.39, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
FAQ
What is the correlation between CBIO and ENSC?
Using weekly returns as of 2026-08-27: 0.39 over 3 years, with 0.18 over the last year and 0.21 over 5 years.
Is ENSC a good diversifier for CBIO?
A fair diversifier. At 0.39, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
What does a correlation of 0.39 mean?
Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/cbio-vs-ensc.json
Markdown for the live badge, attribution link included:
[](https://www.pairbook.io/pair/cbio-vs-ensc/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: CBIO correlations · ENSC correlations
