VTGN vs XBI: Correlation
Vistagen Therapeutics, Inc. (VTGN) and SPDR S&P Biotech ETF (XBI) show a moderate relationship: their 3-year correlation of weekly returns is 0.36.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are VTGN and XBI?
Across a 3-year window, the weekly returns of VTGN and XBI correlate at 0.36, moderate. Lately the two have drifted apart, with the 1-year correlation at 0.20 versus 0.36 over 3 years. Stretching to 5 years gives 0.19, with an annualized covariance of 886.7 %².
Within VTGN's tracked universe of 10 assets, XBI comes in at #5 by 3-year correlation. Their recent paths diverged sharply: over the last 12 months XBI outperformed by 179.1 percentage points (-91.9% for VTGN against +87.2% for XBI). Note the risk asymmetry: VTGN runs 3.3 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
VTGN vs XBI: side by side
| VTGN (Vistagen Therapeutics, Inc.) | XBI (SPDR S&P Biotech ETF) | |
|---|---|---|
| 1-year return | -91.9% | +87.2% |
| 5-year return | -99.7% | +28.6% |
| Volatility (ann.) | 90.2% | 27.7% |
| Beta vs S&P 500 | 0.98 | 1.09 |
| Max drawdown (3Y) | -96.6% | -33.0% |
| Market cap | – | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | – |
| Sector / category | US Listed | ETF · Thematic |
Year-by-year returns
| Year | VTGN | XBI |
|---|---|---|
| 2022 | -94.9% | -25.9% |
| 2023 | +71.3% | +7.6% |
| 2024 | -42.6% | +1.0% |
| 2025 | -77.6% | +35.9% |
| 2026 | -61.1% | +38.1% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are VTGN and XBI good diversifiers for each other?
Yes, to a useful degree: a correlation of 0.36 leaves real independence between the two, which historically damped combined volatility.
FAQ
What is the correlation between VTGN and XBI?
The VTGN/XBI correlation stands at 0.36 on a 3-year window (1 year: 0.20, 5 years: 0.19), computed from weekly returns as of 2026-08-27.
Is XBI a good diversifier for VTGN?
Yes, to a useful degree: a correlation of 0.36 leaves real independence between the two, which historically damped combined volatility.
What does a correlation of 0.36 mean?
Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/vtgn-vs-xbi.json
Embed this badge (it refreshes with the data), with attribution:
[](https://www.pairbook.io/pair/vtgn-vs-xbi/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: VTGN correlations · XBI correlations
