VRTX vs VXZ: Correlation
Measured on weekly returns over the past three years, Vertex Pharmaceuticals (VRTX) and iPath Series B S&P 500 VIX Mid-Term Futures ETN (VXZ) carry a correlation of -0.29, a negative link.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are VRTX and VXZ?
Across a 3-year window, the weekly returns of VRTX and VXZ correlate at -0.29, negative, meaning they tend to move in opposite directions. Recent behaviour matches the longer record: -0.34 over 1 year against -0.29 over 3. Stretching to 5 years gives -0.28, with an annualized covariance of -227.2 %².
VXZ is close to the least connected end of VRTX's tracked universe, ranking #31 of 31. Their recent paths diverged sharply: over the last 12 months VRTX outperformed by 56.8 percentage points (+40.7% for VRTX against -16.1% for VXZ).
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
VRTX vs VXZ: side by side
| VRTX (Vertex Pharmaceuticals) | VXZ (iPath Series B S&P 500 VIX Mid-Term Futures ETN) | |
|---|---|---|
| 1-year return | +40.7% | -16.1% |
| 5-year return | +174.5% | -53.1% |
| Volatility (ann.) | 30.3% | 25.6% |
| Beta vs S&P 500 | 0.55 | -1.31 |
| Max drawdown (3Y) | -29.1% | -36.4% |
| Market cap | $138.8B | – |
| P/E (trailing) | 31.9 | – |
| Dividend yield | 0.00% | – |
| Sector / category | Health Care | US Listed |
Year-by-year returns
| Year | VRTX | VXZ |
|---|---|---|
| 2022 | +31.5% | +0.5% |
| 2023 | +40.9% | -44.0% |
| 2024 | -1.0% | -12.7% |
| 2025 | +12.6% | +5.7% |
| 2026 | +20.8% | -10.5% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are VRTX and VXZ good diversifiers for each other?
Yes: at -0.29, the two have gone their own ways historically, which is what genuine diversification looks like.
FAQ
What is the correlation between VRTX and VXZ?
The VRTX/VXZ correlation stands at -0.29 on a 3-year window (1 year: -0.34, 5 years: -0.28), computed from weekly returns as of 2026-08-27.
Is VXZ a good diversifier for VRTX?
Yes: at -0.29, the two have gone their own ways historically, which is what genuine diversification looks like.
What does a correlation of -0.29 mean?
Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/vrtx-vs-vxz.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/vrtx-vs-vxz/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: VRTX correlations · VXZ correlations
