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VRDN vs XBI: Correlation

How closely do Viridian Therapeutics, Inc. (VRDN) and SPDR S&P Biotech ETF (XBI) trade together? Their weekly returns over three years give a correlation of 0.55, which is moderate.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.55
moderate
Correlation (1Y)
0.25
last 12 months
Correlation (5Y)
0.39
long-run
Ann. covariance
1009.8
%² · weekly, annualized

How correlated are VRDN and XBI?

Over the past 3 years, VRDN and XBI moved with a correlation of 0.55, which is moderate. The link has loosened recently: the 1-year correlation (0.25) runs below the 3-year figure (0.55). Over 5 years the correlation is 0.39, and the annualized covariance of weekly returns is 1009.8 %².

Few assets follow VRDN as closely as XBI, which ranks #1 of 10 tracked partners. The last year tells two different stories: XBI led by 58.5 percentage points, +28.7% for VRDN against +87.2% for XBI. Note the risk asymmetry: VRDN runs 2.4 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

VRDN vs XBI: side by side

VRDN (Viridian Therapeutics, Inc.)XBI (SPDR S&P Biotech ETF)
1-year return+28.7%+87.2%
5-year return+80.0%+28.6%
Volatility (ann.)66.8%27.7%
Beta vs S&P 5001.271.09
Max drawdown (3Y)-60.6%-33.0%
Market cap$2.7B
P/E (trailing)
Dividend yield0.00%
Sector / categoryUS ListedETF · Thematic
Smaller drawdown: XBI -33.0% vs -60.6%Higher 5y return: VRDN +80.0% vs +28.6%
-28%0%+78%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. VRDN · XBI

Year-by-year returns

YearVRDNXBI
2022+47.7%-25.9%
2023-25.4%+7.6%
2024-12.0%+1.0%
2025+62.3%+35.9%
2026-23.3%+38.1%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are VRDN and XBI good diversifiers for each other?

Only partially. A correlation of 0.55 means VRDN and XBI share most of their swings. Pairing them dampens volatility somewhat, but it will not protect against a common drawdown.

FAQ

What is the correlation between VRDN and XBI?

As of 2026-08-27, the correlation of weekly returns between VRDN and XBI is 0.55 over 3 years, 0.25 over 1 year and 0.39 over 5 years.

Is XBI a good diversifier for VRDN?

Only partially. A correlation of 0.55 means VRDN and XBI share most of their swings. Pairing them dampens volatility somewhat, but it will not protect against a common drawdown.

What does a correlation of 0.55 mean?

A reading of 0.55 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.

Use this data

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$ curl https://www.pairbook.io/api/v1/pairs/vrdn-vs-xbi.json

VRDN vs XBI: 3-year weekly correlation 0.55VRDN vs XBI0.55

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Related comparisons

Hubs: VRDN correlations · XBI correlations