UNCY vs XBI: Correlation
Unicycive Therapeutics, Inc. (UNCY) and SPDR S&P Biotech ETF (XBI) show a moderate relationship: their 3-year correlation of weekly returns is 0.36.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are UNCY and XBI?
Over the past 3 years, UNCY and XBI moved with a correlation of 0.36, which is moderate. Recent behaviour matches the longer record: 0.36 over 1 year against 0.36 over 3. Over 5 years the correlation is -0.03, and the annualized covariance of weekly returns is 880.6 %².
By 3-year correlation, XBI places #5 of the 10 assets tracked against UNCY. Correlation aside, the last 12 months split them widely, with XBI ahead by 58.4 points (+28.8% versus +87.2%). One caveat on sizing: UNCY is 3.2 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
UNCY vs XBI: side by side
| UNCY (Unicycive Therapeutics, Inc.) | XBI (SPDR S&P Biotech ETF) | |
|---|---|---|
| 1-year return | +28.8% | +87.2% |
| 5-year return | -79.6% | +28.6% |
| Volatility (ann.) | 88.4% | 27.7% |
| Beta vs S&P 500 | 1.38 | 1.09 |
| Max drawdown (3Y) | -86.8% | -33.0% |
| Market cap | $0.2B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | – |
| Sector / category | US Listed | ETF · Thematic |
Year-by-year returns
| Year | UNCY | XBI |
|---|---|---|
| 2022 | -73.8% | -25.9% |
| 2023 | +60.7% | +7.6% |
| 2024 | -8.5% | +1.0% |
| 2025 | -27.3% | +35.9% |
| 2026 | -4.7% | +38.1% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are UNCY and XBI good diversifiers for each other?
Reasonably. At 0.36, UNCY and XBI keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
FAQ
What is the correlation between UNCY and XBI?
Using weekly returns as of 2026-08-27: 0.36 over 3 years, with 0.36 over the last year and -0.03 over 5 years.
Is XBI a good diversifier for UNCY?
Reasonably. At 0.36, UNCY and XBI keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
What does a correlation of 0.36 mean?
A reading of 0.36 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/uncy-vs-xbi.json
Embed this badge (it refreshes with the data), with attribution:
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Related comparisons
Hubs: UNCY correlations · XBI correlations
