TSHA vs XBI: Correlation
Measured on weekly returns over the past three years, Taysha Gene Therapies, Inc. (TSHA) and SPDR S&P Biotech ETF (XBI) carry a correlation of 0.47, a moderate link.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are TSHA and XBI?
Across a 3-year window, the weekly returns of TSHA and XBI correlate at 0.47, moderate. The past 12 months show a tighter link (0.59) than the 3-year average (0.47). Stretching to 5 years gives 0.36, with an annualized covariance of 1323.9 %².
Few assets follow TSHA as closely as XBI, which ranks #1 of 14 tracked partners. Over the last 12 months TSHA came out ahead by 13.5 percentage points (+100.7% against +87.2%). One caveat on sizing: TSHA is 3.7 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
TSHA vs XBI: side by side
| TSHA (Taysha Gene Therapies, Inc.) | XBI (SPDR S&P Biotech ETF) | |
|---|---|---|
| 1-year return | +100.7% | +87.2% |
| 5-year return | -69.5% | +28.6% |
| Volatility (ann.) | 101.5% | 27.7% |
| Beta vs S&P 500 | 2.63 | 1.09 |
| Max drawdown (3Y) | -72.9% | -33.0% |
| Market cap | $1.9B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | – |
| Sector / category | US Listed | ETF · Thematic |
Year-by-year returns
| Year | TSHA | XBI |
|---|---|---|
| 2022 | -80.6% | -25.9% |
| 2023 | -21.7% | +7.6% |
| 2024 | -2.3% | +1.0% |
| 2025 | +217.9% | +35.9% |
| 2026 | +8.4% | +38.1% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are TSHA and XBI good diversifiers for each other?
A fair diversifier. At 0.47, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
FAQ
What is the correlation between TSHA and XBI?
Using weekly returns as of 2026-08-27: 0.47 over 3 years, with 0.59 over the last year and 0.36 over 5 years.
Is XBI a good diversifier for TSHA?
A fair diversifier. At 0.47, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
What does a correlation of 0.47 mean?
Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/tsha-vs-xbi.json
Embed this badge (it refreshes with the data), with attribution:
[](https://www.pairbook.io/pair/tsha-vs-xbi/)
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Related comparisons
Hubs: TSHA correlations · XBI correlations
