TGTX vs XBI: Correlation
How closely do TG Therapeutics, Inc. (TGTX) and SPDR S&P Biotech ETF (XBI) trade together? Their weekly returns over three years give a correlation of 0.53, which is moderate.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are TGTX and XBI?
Over the past 3 years, TGTX and XBI moved with a correlation of 0.53, which is moderate. The link has loosened recently: the 1-year correlation (0.37) runs below the 3-year figure (0.53). Over 5 years the correlation is 0.54, and the annualized covariance of weekly returns is 1003.3 %².
XBI is one of the assets that tracks TGTX most closely: it ranks #1 out of the 11 assets we track against TGTX. The trailing year gives TGTX the advantage: +95.0% versus +87.2%, a 7.8-point spread. Note the risk asymmetry: TGTX runs 2.5 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
TGTX vs XBI: side by side
| TGTX (TG Therapeutics, Inc.) | XBI (SPDR S&P Biotech ETF) | |
|---|---|---|
| 1-year return | +95.0% | +87.2% |
| 5-year return | +108.6% | +28.6% |
| Volatility (ann.) | 68.7% | 27.7% |
| Beta vs S&P 500 | 1.09 | 1.09 |
| Max drawdown (3Y) | -42.0% | -33.0% |
| Market cap | $8.5B | – |
| P/E (trailing) | 20.1 | – |
| Dividend yield | 0.00% | – |
| Sector / category | US Listed | ETF · Thematic |
Year-by-year returns
| Year | TGTX | XBI |
|---|---|---|
| 2022 | -37.7% | -25.9% |
| 2023 | +44.4% | +7.6% |
| 2024 | +76.2% | +1.0% |
| 2025 | -1.0% | +35.9% |
| 2026 | +86.9% | +38.1% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are TGTX and XBI good diversifiers for each other?
To a limited degree. At 0.53 the two still catch most of the same waves, so the pair smooths returns a little without insulating either from a shared selloff.
FAQ
What is the correlation between TGTX and XBI?
Using weekly returns as of 2026-08-27: 0.53 over 3 years, with 0.37 over the last year and 0.54 over 5 years.
Is XBI a good diversifier for TGTX?
To a limited degree. At 0.53 the two still catch most of the same waves, so the pair smooths returns a little without insulating either from a shared selloff.
What does a correlation of 0.53 mean?
On the −1 to +1 scale, 0.53 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
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Related comparisons
Hubs: TGTX correlations · XBI correlations
