SRPT vs XBI: Correlation
Measured on weekly returns over the past three years, Sarepta Therapeutics, Inc. (SRPT) and SPDR S&P Biotech ETF (XBI) carry a correlation of 0.38, a moderate link.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are SRPT and XBI?
Over the past 3 years, SRPT and XBI moved with a correlation of 0.38, which is moderate. The link has tightened recently: the 1-year correlation (0.54) runs above the 3-year figure (0.38). Over 5 years the correlation is 0.39, and the annualized covariance of weekly returns is 804.0 %².
By 3-year correlation, XBI places #5 of the 13 assets tracked against SRPT. Their recent paths diverged sharply: over the last 12 months XBI outperformed by 67.7 percentage points (+19.5% for SRPT against +87.2% for XBI). One caveat on sizing: SRPT is 2.7 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
SRPT vs XBI: side by side
| SRPT (Sarepta Therapeutics, Inc.) | XBI (SPDR S&P Biotech ETF) | |
|---|---|---|
| 1-year return | +19.5% | +87.2% |
| 5-year return | -71.5% | +28.6% |
| Volatility (ann.) | 75.7% | 27.7% |
| Beta vs S&P 500 | 1.09 | 1.09 |
| Max drawdown (3Y) | -92.7% | -33.0% |
| Market cap | $2.3B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | – |
| Sector / category | US Listed | ETF · Thematic |
Year-by-year returns
| Year | SRPT | XBI |
|---|---|---|
| 2022 | +43.9% | -25.9% |
| 2023 | -25.6% | +7.6% |
| 2024 | +26.1% | +1.0% |
| 2025 | -82.3% | +35.9% |
| 2026 | +0.3% | +38.1% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are SRPT and XBI good diversifiers for each other?
Reasonably. At 0.38, SRPT and XBI keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
FAQ
What is the correlation between SRPT and XBI?
As of 2026-08-27, the correlation of weekly returns between SRPT and XBI is 0.38 over 3 years, 0.54 over 1 year and 0.39 over 5 years.
Is XBI a good diversifier for SRPT?
Reasonably. At 0.38, SRPT and XBI keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
What does a correlation of 0.38 mean?
On the −1 to +1 scale, 0.38 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
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Related comparisons
Hubs: SRPT correlations · XBI correlations
