RNAZ vs TEM: Correlation
TransCode Therapeutics, Inc. (RNAZ) and Tempus AI, Inc. (TEM) show a moderate relationship: their 3-year correlation of weekly returns is 0.40.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are RNAZ and TEM?
Across a 3-year window, the weekly returns of RNAZ and TEM correlate at 0.40, moderate. Lately the two have drifted apart, with the 1-year correlation at 0.19 versus 0.40 over 3 years. Stretching to 5 years gives n/a, with an annualized covariance of 7253.6 %².
Few assets follow RNAZ as closely as TEM, which ranks #1 of 10 tracked partners. Correlation aside, the last 12 months split them widely, with TEM ahead by 73.8 points (-77.3% versus -3.5%). Note the risk asymmetry: RNAZ runs 1.7 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
RNAZ vs TEM: side by side
| RNAZ (TransCode Therapeutics, Inc.) | TEM (Tempus AI, Inc.) | |
|---|---|---|
| 1-year return | -77.3% | -3.5% |
| 5-year return | -100.0% | n/a |
| Volatility (ann.) | 173.5% | 104.7% |
| Beta vs S&P 500 | 2.47 | 3.25 |
| Max drawdown (3Y) | -100.0% | -59.8% |
| Market cap | – | $12.8B |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | RNAZ | TEM |
|---|---|---|
| 2022 | -73.5% | – |
| 2023 | -98.8% | – |
| 2024 | -98.5% | – |
| 2025 | -92.8% | +74.9% |
| 2026 | -66.6% | +19.7% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are RNAZ and TEM good diversifiers for each other?
Yes, to a useful degree: a correlation of 0.40 leaves real independence between the two, which historically damped combined volatility.
FAQ
What is the correlation between RNAZ and TEM?
The RNAZ/TEM correlation stands at 0.40 on a 3-year window (1 year: 0.19, 5 years: n/a), computed from weekly returns as of 2026-08-27.
Is TEM a good diversifier for RNAZ?
Yes, to a useful degree: a correlation of 0.40 leaves real independence between the two, which historically damped combined volatility.
What does a correlation of 0.40 mean?
Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/rnaz-vs-tem.json
Embed this badge (it refreshes with the data), with attribution:
[](https://www.pairbook.io/pair/rnaz-vs-tem/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: RNAZ correlations · TEM correlations
