RGNX vs XBI: Correlation
REGENXBIO Inc. (RGNX) and SPDR S&P Biotech ETF (XBI) show a strong relationship: their 3-year correlation of weekly returns is 0.62.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are RGNX and XBI?
Across a 3-year window, the weekly returns of RGNX and XBI correlate at 0.62, strong. The relationship has been stable: the 1-year correlation (0.69) sits close to the 3-year figure. Stretching to 5 years gives 0.59, with an annualized covariance of 1435.2 %².
In RGNX's tracked universe of 14 assets, XBI sits right near the top at #1. The last year tells two different stories: XBI led by 81.0 percentage points, +6.2% for RGNX against +87.2% for XBI. Note the risk asymmetry: RGNX runs 3.0 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
RGNX vs XBI: side by side
| RGNX (REGENXBIO Inc.) | XBI (SPDR S&P Biotech ETF) | |
|---|---|---|
| 1-year return | +6.2% | +87.2% |
| 5-year return | -70.5% | +28.6% |
| Volatility (ann.) | 84.1% | 27.7% |
| Beta vs S&P 500 | 2.28 | 1.09 |
| Max drawdown (3Y) | -78.4% | -33.0% |
| Market cap | $0.6B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | – |
| Sector / category | US Listed | ETF · Thematic |
Year-by-year returns
| Year | RGNX | XBI |
|---|---|---|
| 2022 | -30.6% | -25.9% |
| 2023 | -20.9% | +7.6% |
| 2024 | -56.9% | +1.0% |
| 2025 | +86.3% | +35.9% |
| 2026 | -34.9% | +38.1% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are RGNX and XBI good diversifiers for each other?
Only partially. A correlation of 0.62 means RGNX and XBI share most of their swings. Pairing them dampens volatility somewhat, but it will not protect against a common drawdown.
FAQ
What is the correlation between RGNX and XBI?
Using weekly returns as of 2026-08-27: 0.62 over 3 years, with 0.69 over the last year and 0.59 over 5 years.
Is XBI a good diversifier for RGNX?
Only partially. A correlation of 0.62 means RGNX and XBI share most of their swings. Pairing them dampens volatility somewhat, but it will not protect against a common drawdown.
What does a correlation of 0.62 mean?
On the −1 to +1 scale, 0.62 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/rgnx-vs-xbi.json
Embed this badge (it refreshes with the data), with attribution:
[](https://www.pairbook.io/pair/rgnx-vs-xbi/)
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Related comparisons
Hubs: RGNX correlations · XBI correlations
