RGNX vs SPY: Correlation
REGENXBIO Inc. (RGNX) and SPDR S&P 500 ETF Trust (SPY) show a moderate relationship: their 3-year correlation of weekly returns is 0.39.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are RGNX and SPY?
On 3 years of weekly data the RGNX/SPY correlation comes out at 0.39, moderate. The relationship has been stable: the 1-year correlation (0.33) sits close to the 3-year figure. The 5-year figure is 0.38, and annualized covariance runs at 476.8 %².
Among the 14 assets we track against RGNX, SPY ranks #9 by 3-year correlation. The trailing year gives SPY the advantage: +6.2% versus +20.6%, a 14.4-point spread. One caveat on sizing: RGNX is 5.8 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
RGNX vs SPY: side by side
| RGNX (REGENXBIO Inc.) | SPY (SPDR S&P 500 ETF Trust) | |
|---|---|---|
| 1-year return | +6.2% | +20.6% |
| 5-year return | -70.5% | +82.4% |
| Volatility (ann.) | 84.1% | 14.5% |
| Beta vs S&P 500 | 2.28 | 1.00 |
| Max drawdown (3Y) | -78.4% | -18.8% |
| Market cap | $0.6B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 1.01% |
| Expense ratio | – | 0.09% |
| Assets under management | – | $795.3B |
| Sector / category | US Listed | ETF · US Large Cap |
SPY is a Large Blend fund from State Street Investment Management: $795.3B under management, 504 holdings, a 0.09% expense ratio, a 1.01% trailing dividend yield.
Year-by-year returns
| Year | RGNX | SPY |
|---|---|---|
| 2022 | -30.6% | -18.2% |
| 2023 | -20.9% | +26.2% |
| 2024 | -56.9% | +24.9% |
| 2025 | +86.3% | +17.7% |
| 2026 | -34.9% | +13.7% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are RGNX and SPY good diversifiers for each other?
Yes, to a useful degree: a correlation of 0.39 leaves real independence between the two, which historically damped combined volatility.
FAQ
What is the correlation between RGNX and SPY?
Using weekly returns as of 2026-08-27: 0.39 over 3 years, with 0.33 over the last year and 0.38 over 5 years.
Is SPY a good diversifier for RGNX?
Yes, to a useful degree: a correlation of 0.39 leaves real independence between the two, which historically damped combined volatility.
What does a correlation of 0.39 mean?
On the −1 to +1 scale, 0.39 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
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Related comparisons
Hubs: RGNX correlations · SPY correlations
