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RF vs SPRB: Correlation

How closely do Regions Financial Corporation (RF) and Spruce Biosciences, Inc. (SPRB) trade together? Their weekly returns over three years give a correlation of -0.16, which is negative.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
-0.16
negative
Correlation (1Y)
-0.37
last 12 months
Correlation (5Y)
-0.11
long-run
Ann. covariance
-5176.6
%² · weekly, annualized

How correlated are RF and SPRB?

Over the past 3 years, RF and SPRB moved with a correlation of -0.16, which is negative, meaning they tend to move in opposite directions. The link has loosened recently: the 1-year correlation (-0.37) runs below the 3-year figure (-0.16). Over 5 years the correlation is -0.11, and the annualized covariance of weekly returns is -5176.6 %².

Among the 44 assets we track against RF, SPRB sits near the bottom by co-movement, at rank #41. Their recent paths diverged sharply: over the last 12 months SPRB outperformed by 730.9 percentage points (+15.4% for RF against +746.3% for SPRB). Risk is not evenly split, since SPRB carries 37.2 times the volatility of the other side.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

RF vs SPRB: side by side

RF (Regions Financial Corporation)SPRB (Spruce Biosciences, Inc.)
1-year return+15.4%+746.3%
5-year return+83.5%-99.8%
Volatility (ann.)29.2%1086.4%
Beta vs S&P 5001.09-7.82
Max drawdown (3Y)-31.9%-100.0%
Market cap$25.9B$0.2B
P/E (trailing)12.4
Dividend yield3.45%0.00%
Sector / categoryFinancialsUS Listed
Higher yield: RF 3.45% vs 0.00%Smaller drawdown: RF -31.9% vs -100.0%Higher 5y return: RF +83.5% vs -99.8%
-14%0%+1829%2025-09-052026-08-27
Twelve months of weekly closes, each series rebased to 100. RF · SPRB

Year-by-year returns

YearRFSPRB
2022+2.3%-75.4%
2023-5.7%+167.1%
2024+27.0%-85.7%
2025+20.2%-96.3%
2026+14.3%-27.3%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are RF and SPRB good diversifiers for each other?

By historical standards, yes. A correlation of -0.16 means the two rarely move for the same reasons.

FAQ

What is the correlation between RF and SPRB?

As of 2026-08-27, the correlation of weekly returns between RF and SPRB is -0.16 over 3 years, -0.37 over 1 year and -0.11 over 5 years.

Is SPRB a good diversifier for RF?

By historical standards, yes. A correlation of -0.16 means the two rarely move for the same reasons.

What does a correlation of -0.16 mean?

Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.

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RF vs SPRB: 3-year weekly correlation -0.16RF vs SPRB-0.16

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Related comparisons

Hubs: RF correlations · SPRB correlations