PRME vs QQQ: Correlation
Measured on weekly returns over the past three years, Prime Medicine, Inc. (PRME) and Invesco QQQ Trust (QQQ) carry a correlation of 0.39, a moderate link.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are PRME and QQQ?
On 3 years of weekly data the PRME/QQQ correlation comes out at 0.39, moderate. The past 12 months show a weaker link (0.29) than the 3-year average (0.39). The 5-year figure is 0.36, and annualized covariance runs at 762.1 %².
Within PRME's tracked universe of 18 assets, QQQ comes in at #13 by 3-year correlation. Their recent paths diverged sharply: over the last 12 months QQQ outperformed by 20.2 percentage points (+6.1% for PRME against +26.3% for QQQ). Note the risk asymmetry: PRME runs 5.0 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
PRME vs QQQ: side by side
| PRME (Prime Medicine, Inc.) | QQQ (Invesco QQQ Trust) | |
|---|---|---|
| 1-year return | +6.1% | +26.3% |
| 5-year return | n/a | +95.4% |
| Volatility (ann.) | 98.7% | 19.6% |
| Beta vs S&P 500 | 2.97 | 1.28 |
| Max drawdown (3Y) | -91.4% | -22.8% |
| Market cap | $0.7B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.44% |
| Expense ratio | – | 0.18% |
| Assets under management | – | $452.8B |
| Sector / category | US Listed | ETF · US Growth & Tech |
QQQ is a Large Growth fund from Invesco: $452.8B under management, 104 holdings, a 0.18% expense ratio, a 0.44% trailing dividend yield.
Year-by-year returns
| Year | PRME | QQQ |
|---|---|---|
| 2022 | – | -32.6% |
| 2023 | -52.3% | +54.9% |
| 2024 | -67.0% | +25.6% |
| 2025 | +18.8% | +20.8% |
| 2026 | +4.9% | +17.7% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are PRME and QQQ good diversifiers for each other?
Reasonably. At 0.39, PRME and QQQ keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
FAQ
What is the correlation between PRME and QQQ?
The PRME/QQQ correlation stands at 0.39 on a 3-year window (1 year: 0.29, 5 years: 0.36), computed from weekly returns as of 2026-08-27.
Is QQQ a good diversifier for PRME?
Reasonably. At 0.39, PRME and QQQ keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
What does a correlation of 0.39 mean?
A reading of 0.39 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/prme-vs-qqq.json
Embed this badge (it refreshes with the data), with attribution:
[](https://www.pairbook.io/pair/prme-vs-qqq/)
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Related comparisons
Hubs: PRME correlations · QQQ correlations
