CRSP vs PRME: Correlation
CRISPR Therapeutics AG (CRSP) and Prime Medicine, Inc. (PRME) show a strong relationship: their 3-year correlation of weekly returns is 0.60.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are CRSP and PRME?
Across a 3-year window, the weekly returns of CRSP and PRME correlate at 0.60, strong. The relationship has been stable: the 1-year correlation (0.67) sits close to the 3-year figure. Stretching to 5 years gives 0.55, with an annualized covariance of 3482.7 %².
By 3-year correlation, PRME places #6 of the 19 assets tracked against CRSP. Their 12-month results are close: +10.9% for CRSP against +6.1% for PRME. Risk is not evenly split, since PRME carries 1.7 times the volatility of the other side.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
CRSP vs PRME: side by side
| CRSP (CRISPR Therapeutics AG) | PRME (Prime Medicine, Inc.) | |
|---|---|---|
| 1-year return | +10.9% | +6.1% |
| 5-year return | -50.8% | n/a |
| Volatility (ann.) | 58.5% | 98.7% |
| Beta vs S&P 500 | 2.10 | 2.97 |
| Max drawdown (3Y) | -64.9% | -91.4% |
| Market cap | $5.7B | $0.7B |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | CRSP | PRME |
|---|---|---|
| 2022 | -46.4% | – |
| 2023 | +54.0% | -52.3% |
| 2024 | -37.1% | -67.0% |
| 2025 | +33.2% | +18.8% |
| 2026 | +13.2% | +4.9% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are CRSP and PRME good diversifiers for each other?
Somewhat, no more. With 0.60 correlation, most large moves hit both names, and the diversification benefit stays modest.
FAQ
What is the correlation between CRSP and PRME?
Using weekly returns as of 2026-08-27: 0.60 over 3 years, with 0.67 over the last year and 0.55 over 5 years.
Is PRME a good diversifier for CRSP?
Somewhat, no more. With 0.60 correlation, most large moves hit both names, and the diversification benefit stays modest.
What does a correlation of 0.60 mean?
Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/crsp-vs-prme.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/crsp-vs-prme/)
Free with attribution; caching and terms are described in the API documentation.
Related comparisons
Hubs: CRSP correlations · PRME correlations
