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MDXH vs SPY: Correlation

How closely do MDxHealth SA (MDXH) and SPDR S&P 500 ETF Trust (SPY) trade together? Their weekly returns over three years give a correlation of 0.33, which is moderate.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.33
moderate
Correlation (1Y)
0.33
last 12 months
Correlation (5Y)
0.19
long-run
Ann. covariance
411.6
%² · weekly, annualized

How correlated are MDXH and SPY?

Over the past 3 years, MDXH and SPY moved with a correlation of 0.33, which is moderate. Recent behaviour matches the longer record: 0.33 over 1 year against 0.33 over 3. Over 5 years the correlation is 0.19, and the annualized covariance of weekly returns is 411.6 %².

Out of 14 assets tracked against MDXH, SPY lands near the bottom at #11. Their recent paths diverged sharply: over the last 12 months SPY outperformed by 100.5 percentage points (-79.9% for MDXH against +20.6% for SPY). One caveat on sizing: MDXH is 6.0 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

MDXH vs SPY: side by side

MDXH (MDxHealth SA)SPY (SPDR S&P 500 ETF Trust)
1-year return-79.9%+20.6%
5-year return-94.0%+82.4%
Volatility (ann.)86.5%14.5%
Beta vs S&P 5001.971.00
Max drawdown (3Y)-92.0%-18.8%
Market cap$0.1B
P/E (trailing)
Dividend yield0.00%1.01%
Expense ratio0.09%
Assets under management$795.3B
Sector / categoryUS ListedETF · US Large Cap
Higher yield: SPY 1.01% vs 0.00%Smaller drawdown: SPY -18.8% vs -92.0%Higher 5y return: SPY +82.4% vs -94.0%

SPY is a Large Blend fund from State Street Investment Management: $795.3B under management, 504 holdings, a 0.09% expense ratio, a 1.01% trailing dividend yield.

-88%0%+39%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. MDXH · SPY

Year-by-year returns

YearMDXHSPY
2022-30.6%-18.2%
2023-40.4%+26.2%
2024-39.8%+24.9%
2025+50.6%+17.7%
2026-79.8%+13.7%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are MDXH and SPY good diversifiers for each other?

Yes, to a useful degree: a correlation of 0.33 leaves real independence between the two, which historically damped combined volatility.

FAQ

What is the correlation between MDXH and SPY?

Using weekly returns as of 2026-08-27: 0.33 over 3 years, with 0.33 over the last year and 0.19 over 5 years.

Is SPY a good diversifier for MDXH?

Yes, to a useful degree: a correlation of 0.33 leaves real independence between the two, which historically damped combined volatility.

What does a correlation of 0.33 mean?

Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.

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MDXH vs SPY: 3-year weekly correlation 0.33MDXH vs SPY0.33

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Hubs: MDXH correlations · SPY correlations