IRON vs RYTM: Correlation
Measured on weekly returns over the past three years, Disc Medicine, Inc. (IRON) and Rhythm Pharmaceuticals, Inc. (RYTM) carry a correlation of 0.43, a moderate link.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are IRON and RYTM?
Over the past 3 years, IRON and RYTM moved with a correlation of 0.43, which is moderate. Little has changed lately, as the 1-year reading of 0.35 lands near the 3-year figure. Over 5 years the correlation is 0.22, and the annualized covariance of weekly returns is 1483.7 %².
Among the 15 assets we track against IRON, RYTM ranks #5 by 3-year correlation. Correlation aside, the last 12 months split them widely, with IRON ahead by 27.7 points (+37.7% versus +10.0%).
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
IRON vs RYTM: side by side
| IRON (Disc Medicine, Inc.) | RYTM (Rhythm Pharmaceuticals, Inc.) | |
|---|---|---|
| 1-year return | +37.7% | +10.0% |
| 5-year return | -32.4% | +785.4% |
| Volatility (ann.) | 59.7% | 58.4% |
| Beta vs S&P 500 | 1.70 | 1.92 |
| Max drawdown (3Y) | -64.8% | -35.5% |
| Market cap | $3.2B | $7.7B |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | IRON | RYTM |
|---|---|---|
| 2022 | -77.2% | +191.8% |
| 2023 | +190.4% | +57.9% |
| 2024 | +9.8% | +21.8% |
| 2025 | +25.3% | +91.2% |
| 2026 | +4.0% | +5.1% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are IRON and RYTM good diversifiers for each other?
Yes, to a useful degree: a correlation of 0.43 leaves real independence between the two, which historically damped combined volatility.
FAQ
What is the correlation between IRON and RYTM?
Using weekly returns as of 2026-08-27: 0.43 over 3 years, with 0.35 over the last year and 0.22 over 5 years.
Is RYTM a good diversifier for IRON?
Yes, to a useful degree: a correlation of 0.43 leaves real independence between the two, which historically damped combined volatility.
What does a correlation of 0.43 mean?
Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/iron-vs-rytm.json
Markdown for the live badge, attribution link included:
[](https://www.pairbook.io/pair/iron-vs-rytm/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: IRON correlations · RYTM correlations
