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ICU vs SRPT: Correlation

Measured on weekly returns over the past three years, SeaStar Medical Holding Corporation (ICU) and Sarepta Therapeutics, Inc. (SRPT) carry a correlation of 0.29, a weak link.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.29
weak
Correlation (1Y)
0.40
last 12 months
Correlation (5Y)
0.24
long-run
Ann. covariance
3474.8
%² · weekly, annualized

How correlated are ICU and SRPT?

On 3 years of weekly data the ICU/SRPT correlation comes out at 0.29, weak. Lately the two have moved closer together, with the 1-year correlation at 0.40 versus 0.29 over 3 years. The 5-year figure is 0.24, and annualized covariance runs at 3474.8 %².

SRPT is one of the assets that tracks ICU most closely: it ranks #2 out of the 10 assets we track against ICU. Their recent paths diverged sharply: over the last 12 months SRPT outperformed by 82.9 percentage points (-63.4% for ICU against +19.5% for SRPT). One caveat on sizing: ICU is 2.1 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

ICU vs SRPT: side by side

ICU (SeaStar Medical Holding Corporation)SRPT (Sarepta Therapeutics, Inc.)
1-year return-63.4%+19.5%
5-year return-99.9%-71.5%
Volatility (ann.)156.9%75.7%
Beta vs S&P 5000.821.09
Max drawdown (3Y)-99.4%-92.7%
Market cap$2.3B
P/E (trailing)
Dividend yield0.00%0.00%
Sector / categoryUS ListedUS Listed
Smaller drawdown: SRPT -92.7% vs -99.4%Higher 5y return: SRPT -71.5% vs -99.9%
-72%0%+28%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. ICU · SRPT

Year-by-year returns

YearICUSRPT
2022-59.2%+43.9%
2023-89.2%-25.6%
2024-82.5%+26.1%
2025-87.6%-82.3%
2026+29.2%+0.3%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are ICU and SRPT good diversifiers for each other?

Yes, to a useful degree: a correlation of 0.29 leaves real independence between the two, which historically damped combined volatility.

FAQ

What is the correlation between ICU and SRPT?

Using weekly returns as of 2026-08-27: 0.29 over 3 years, with 0.40 over the last year and 0.24 over 5 years.

Is SRPT a good diversifier for ICU?

Yes, to a useful degree: a correlation of 0.29 leaves real independence between the two, which historically damped combined volatility.

What does a correlation of 0.29 mean?

A reading of 0.29 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.

Use this data

JSON API · no key required
$ curl https://www.pairbook.io/api/v1/pairs/icu-vs-srpt.json

ICU vs SRPT: 3-year weekly correlation 0.29ICU vs SRPT0.29

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Related comparisons

Hubs: ICU correlations · SRPT correlations