ENTA vs XLO: Correlation
How closely do Enanta Pharmaceuticals, Inc. (ENTA) and Xilio Therapeutics, Inc. (XLO) trade together? Their weekly returns over three years give a correlation of 0.36, which is moderate.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are ENTA and XLO?
Over the past 3 years, ENTA and XLO moved with a correlation of 0.36, which is moderate. The link has loosened recently: the 1-year correlation (-0.05) runs below the 3-year figure (0.36). Over 5 years the correlation is 0.30, and the annualized covariance of weekly returns is 2429.0 %².
By 3-year correlation, XLO places #9 of the 15 assets tracked against ENTA. Their recent paths diverged sharply: over the last 12 months ENTA outperformed by 67.8 percentage points (+61.8% for ENTA against -6.0% for XLO).
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
ENTA vs XLO: side by side
| ENTA (Enanta Pharmaceuticals, Inc.) | XLO (Xilio Therapeutics, Inc.) | |
|---|---|---|
| 1-year return | +61.8% | -6.0% |
| 5-year return | -75.7% | -96.0% |
| Volatility (ann.) | 70.9% | 96.4% |
| Beta vs S&P 500 | 1.57 | -0.07 |
| Max drawdown (3Y) | -75.6% | -82.8% |
| Market cap | $0.4B | $0.1B |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | ENTA | XLO |
|---|---|---|
| 2022 | -37.8% | -83.2% |
| 2023 | -79.8% | -79.6% |
| 2024 | -38.9% | +73.6% |
| 2025 | +174.3% | -33.0% |
| 2026 | -12.5% | +0.6% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are ENTA and XLO good diversifiers for each other?
A fair diversifier. At 0.36, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
FAQ
What is the correlation between ENTA and XLO?
The ENTA/XLO correlation stands at 0.36 on a 3-year window (1 year: -0.05, 5 years: 0.30), computed from weekly returns as of 2026-08-27.
Is XLO a good diversifier for ENTA?
A fair diversifier. At 0.36, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
What does a correlation of 0.36 mean?
A reading of 0.36 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/enta-vs-xlo.json
Markdown for the live badge, attribution link included:
[](https://www.pairbook.io/pair/enta-vs-xlo/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: ENTA correlations · XLO correlations
