CRBU vs XBI: Correlation
Caribou Biosciences, Inc. (CRBU) and SPDR S&P Biotech ETF (XBI) show a moderate relationship: their 3-year correlation of weekly returns is 0.59.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are CRBU and XBI?
Over the past 3 years, CRBU and XBI moved with a correlation of 0.59, which is moderate. Recent behaviour matches the longer record: 0.50 over 1 year against 0.59 over 3. Over 5 years the correlation is 0.49, and the annualized covariance of weekly returns is 1317.5 %².
In CRBU's tracked universe of 17 assets, XBI sits right near the top at #1. Correlation aside, the last 12 months split them widely, with XBI ahead by 103.4 points (-16.2% versus +87.2%). Risk is not evenly split, since CRBU carries 2.9 times the volatility of the other side.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
CRBU vs XBI: side by side
| CRBU (Caribou Biosciences, Inc.) | XBI (SPDR S&P Biotech ETF) | |
|---|---|---|
| 1-year return | -16.2% | +87.2% |
| 5-year return | -93.2% | +28.6% |
| Volatility (ann.) | 80.5% | 27.7% |
| Beta vs S&P 500 | 2.52 | 1.09 |
| Max drawdown (3Y) | -91.1% | -33.0% |
| Market cap | $0.2B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | – |
| Sector / category | US Listed | ETF · Thematic |
Year-by-year returns
| Year | CRBU | XBI |
|---|---|---|
| 2022 | -58.4% | -25.9% |
| 2023 | -8.8% | +7.6% |
| 2024 | -72.3% | +1.0% |
| 2025 | +0.0% | +35.9% |
| 2026 | +4.4% | +38.1% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are CRBU and XBI good diversifiers for each other?
Somewhat, no more. With 0.59 correlation, most large moves hit both names, and the diversification benefit stays modest.
FAQ
What is the correlation between CRBU and XBI?
Using weekly returns as of 2026-08-27: 0.59 over 3 years, with 0.50 over the last year and 0.49 over 5 years.
Is XBI a good diversifier for CRBU?
Somewhat, no more. With 0.59 correlation, most large moves hit both names, and the diversification benefit stays modest.
What does a correlation of 0.59 mean?
On the −1 to +1 scale, 0.59 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/crbu-vs-xbi.json
Embed this badge (it refreshes with the data), with attribution:
[](https://www.pairbook.io/pair/crbu-vs-xbi/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: CRBU correlations · XBI correlations
