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CRBU vs MCRB: Correlation

How closely do Caribou Biosciences, Inc. (CRBU) and Seres Therapeutics, Inc. (MCRB) trade together? Their weekly returns over three years give a correlation of 0.39, which is moderate.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.39
moderate
Correlation (1Y)
0.23
last 12 months
Correlation (5Y)
0.33
long-run
Ann. covariance
3262.7
%² · weekly, annualized

How correlated are CRBU and MCRB?

Over the past 3 years, CRBU and MCRB moved with a correlation of 0.39, which is moderate. The past 12 months show a weaker link (0.23) than the 3-year average (0.39). Over 5 years the correlation is 0.33, and the annualized covariance of weekly returns is 3262.7 %².

By 3-year correlation, MCRB places #12 of the 17 assets tracked against CRBU. Correlation aside, the last 12 months split them widely, with CRBU ahead by 57.6 points (-16.2% versus -73.8%).

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

CRBU vs MCRB: side by side

CRBU (Caribou Biosciences, Inc.)MCRB (Seres Therapeutics, Inc.)
1-year return-16.2%-73.8%
5-year return-93.2%-96.0%
Volatility (ann.)80.5%103.2%
Beta vs S&P 5002.521.38
Max drawdown (3Y)-91.1%-94.0%
Market cap$0.2B
P/E (trailing)
Dividend yield0.00%0.00%
Sector / categoryUS ListedUS Listed
Smaller drawdown: CRBU -91.1% vs -94.0%Higher 5y return: CRBU -93.2% vs -96.0%
-76%0%+41%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. CRBU · MCRB

Year-by-year returns

YearCRBUMCRB
2022-58.4%-32.8%
2023-8.8%-75.0%
2024-72.3%-40.6%
2025+0.0%-10.5%
2026+4.4%-66.7%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are CRBU and MCRB good diversifiers for each other?

Reasonably. At 0.39, CRBU and MCRB keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.

FAQ

What is the correlation between CRBU and MCRB?

Using weekly returns as of 2026-08-27: 0.39 over 3 years, with 0.23 over the last year and 0.33 over 5 years.

Is MCRB a good diversifier for CRBU?

Reasonably. At 0.39, CRBU and MCRB keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.

What does a correlation of 0.39 mean?

On the −1 to +1 scale, 0.39 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.

Use this data

JSON API · no key required
$ curl https://www.pairbook.io/api/v1/pairs/crbu-vs-mcrb.json

CRBU vs MCRB: 3-year weekly correlation 0.39CRBU vs MCRB0.39

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Related comparisons

Hubs: CRBU correlations · MCRB correlations