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CLDX vs PTGX: Correlation

How closely do Celldex Therapeutics, Inc. (CLDX) and Protagonist Therapeutics, Inc. (PTGX) trade together? Their weekly returns over three years give a correlation of 0.42, which is moderate.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.42
moderate
Correlation (1Y)
0.32
last 12 months
Correlation (5Y)
0.29
long-run
Ann. covariance
1337.5
%² · weekly, annualized

How correlated are CLDX and PTGX?

Across a 3-year window, the weekly returns of CLDX and PTGX correlate at 0.42, moderate. The relationship has been stable: the 1-year correlation (0.32) sits close to the 3-year figure. Stretching to 5 years gives 0.29, with an annualized covariance of 1337.5 %².

Within CLDX's tracked universe of 18 assets, PTGX comes in at #8 by 3-year correlation. Their recent paths diverged sharply: over the last 12 months PTGX outperformed by 64.4 percentage points (+79.0% for CLDX against +143.4% for PTGX).

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

CLDX vs PTGX: side by side

CLDX (Celldex Therapeutics, Inc.)PTGX (Protagonist Therapeutics, Inc.)
1-year return+79.0%+143.4%
5-year return-21.9%+219.7%
Volatility (ann.)59.4%53.0%
Beta vs S&P 5001.480.49
Max drawdown (3Y)-70.8%-31.6%
Market cap$3.2B$9.7B
P/E (trailing)145.1
Dividend yield0.00%0.00%
Sector / categoryUS ListedUS Listed
Smaller drawdown: PTGX -31.6% vs -70.8%Higher 5y return: PTGX +219.7% vs -21.9%
-3%0%+156%2025-09-052026-08-27
Twelve months of weekly closes, each series rebased to 100. CLDX · PTGX

Year-by-year returns

YearCLDXPTGX
2022+15.3%-68.1%
2023-11.0%+110.2%
2024-36.3%+68.3%
2025+7.5%+126.3%
2026+49.0%+71.2%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are CLDX and PTGX good diversifiers for each other?

Yes, to a useful degree: a correlation of 0.42 leaves real independence between the two, which historically damped combined volatility.

FAQ

What is the correlation between CLDX and PTGX?

Using weekly returns as of 2026-08-27: 0.42 over 3 years, with 0.32 over the last year and 0.29 over 5 years.

Is PTGX a good diversifier for CLDX?

Yes, to a useful degree: a correlation of 0.42 leaves real independence between the two, which historically damped combined volatility.

What does a correlation of 0.42 mean?

A reading of 0.42 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.

Use this data

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CLDX vs PTGX: 3-year weekly correlation 0.42CLDX vs PTGX0.42

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Related comparisons

Hubs: CLDX correlations · PTGX correlations