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BFRI vs SPY: Correlation

How closely do Biofrontera Inc. (BFRI) and SPDR S&P 500 ETF Trust (SPY) trade together? Their weekly returns over three years give a correlation of 0.10, which is weak.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.10
weak
Correlation (1Y)
0.40
last 12 months
Correlation (5Y)
0.11
long-run
Ann. covariance
137.1
%² · weekly, annualized

How correlated are BFRI and SPY?

On 3 years of weekly data the BFRI/SPY correlation comes out at 0.10, weak. Lately the two have moved closer together, with the 1-year correlation at 0.40 versus 0.10 over 3 years. The 5-year figure is 0.11, and annualized covariance runs at 137.1 %².

Out of 10 assets tracked against BFRI, SPY lands near the bottom at #6. Their recent paths diverged sharply: over the last 12 months BFRI outperformed by 52.7 percentage points (+73.3% for BFRI against +20.6% for SPY). One caveat on sizing: BFRI is 6.4 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

BFRI vs SPY: side by side

BFRI (Biofrontera Inc.)SPY (SPDR S&P 500 ETF Trust)
1-year return+73.3%+20.6%
5-year return-98.3%+82.4%
Volatility (ann.)92.3%14.5%
Beta vs S&P 5000.661.00
Max drawdown (3Y)-93.9%-18.8%
Market cap
P/E (trailing)
Dividend yield0.00%1.01%
Expense ratio0.09%
Assets under management$795.3B
Sector / categoryUS ListedETF · US Large Cap
Higher yield: SPY 1.01% vs 0.00%Smaller drawdown: SPY -18.8% vs -93.9%Higher 5y return: SPY +82.4% vs -98.3%

SPY is a Large Blend fund from State Street Investment Management: $795.3B under management, 504 holdings, a 0.09% expense ratio, a 1.01% trailing dividend yield.

-15%0%+76%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. BFRI · SPY

Year-by-year returns

YearBFRISPY
2022-87.8%-18.2%
2023-84.9%+26.2%
2024-60.6%+24.9%
2025-47.7%+17.7%
2026+161.4%+13.7%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are BFRI and SPY good diversifiers for each other?

By historical standards, yes. A correlation of 0.10 means the two rarely move for the same reasons.

FAQ

What is the correlation between BFRI and SPY?

Using weekly returns as of 2026-08-27: 0.10 over 3 years, with 0.40 over the last year and 0.11 over 5 years.

Is SPY a good diversifier for BFRI?

By historical standards, yes. A correlation of 0.10 means the two rarely move for the same reasons.

What does a correlation of 0.10 mean?

On the −1 to +1 scale, 0.10 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.

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BFRI vs SPY: 3-year weekly correlation 0.10BFRI vs SPY0.10

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Hubs: BFRI correlations · SPY correlations