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ASMB vs XBI: Correlation

How closely do Assembly Biosciences, Inc. (ASMB) and SPDR S&P Biotech ETF (XBI) trade together? Their weekly returns over three years give a correlation of 0.39, which is moderate.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.39
moderate
Correlation (1Y)
0.43
last 12 months
Correlation (5Y)
0.40
long-run
Ann. covariance
663.9
%² · weekly, annualized

How correlated are ASMB and XBI?

Across a 3-year window, the weekly returns of ASMB and XBI correlate at 0.39, moderate. The relationship has been stable: the 1-year correlation (0.43) sits close to the 3-year figure. Stretching to 5 years gives 0.40, with an annualized covariance of 663.9 %².

XBI is one of the assets that tracks ASMB most closely: it ranks #2 out of the 11 assets we track against ASMB. Correlation aside, the last 12 months split them widely, with XBI ahead by 52.8 points (+34.4% versus +87.2%). Risk is not evenly split, since ASMB carries 2.2 times the volatility of the other side.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

ASMB vs XBI: side by side

ASMB (Assembly Biosciences, Inc.)XBI (SPDR S&P Biotech ETF)
1-year return+34.4%+87.2%
5-year return-21.2%+28.6%
Volatility (ann.)61.8%27.7%
Beta vs S&P 5001.091.09
Max drawdown (3Y)-57.5%-33.0%
Market cap$0.7B
P/E (trailing)28.5
Dividend yield0.00%
Sector / categoryUS ListedETF · Thematic
Smaller drawdown: XBI -33.0% vs -57.5%Higher 5y return: XBI +28.6% vs -21.2%
-8%0%+77%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. ASMB · XBI

Year-by-year returns

YearASMBXBI
2022-44.2%-25.9%
2023-36.9%+7.6%
2024+60.4%+1.0%
2025+115.5%+35.9%
2026+2.3%+38.1%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are ASMB and XBI good diversifiers for each other?

Yes, to a useful degree: a correlation of 0.39 leaves real independence between the two, which historically damped combined volatility.

FAQ

What is the correlation between ASMB and XBI?

Using weekly returns as of 2026-08-27: 0.39 over 3 years, with 0.43 over the last year and 0.40 over 5 years.

Is XBI a good diversifier for ASMB?

Yes, to a useful degree: a correlation of 0.39 leaves real independence between the two, which historically damped combined volatility.

What does a correlation of 0.39 mean?

On the −1 to +1 scale, 0.39 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.

Use this data

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ASMB vs XBI: 3-year weekly correlation 0.39ASMB vs XBI0.39

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Related comparisons

Hubs: ASMB correlations · XBI correlations